Guffey Darren, Narahari Swetha, Alinia Hossein
Department of Internal Medicine, School of Medicine, University of Virginia, Charlottesville, Virginia.
Center for Dermatology Research, Department of Dermatology, School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
Pediatr Dermatol. 2016 Mar-Apr;33(2):e160-1. doi: 10.1111/pde.12806. Epub 2016 Feb 10.
Although acanthosis nigricans of the posterior neck and intertriginous areas is common, acanthosis nigricans of the supra-alar creases is rare. We present the case of an obese 16-year-old African American boy with hyperpigmented plaques along the supra-alar creases of his nose. Clinicians should be aware of this rare manifestation, because newly diagnosed acanthosis nigricans should prompt examination for insulin resistance.
虽然后颈部和皮肤褶皱处的黑棘皮病很常见,但鼻翼上皱襞处的黑棘皮病却很罕见。我们报告一例16岁肥胖非裔美国男孩的病例,其鼻翼上皱襞处有色素沉着斑。临床医生应注意这种罕见表现,因为新诊断的黑棘皮病应促使对胰岛素抵抗进行检查。