Wilson S E, Lin D T, Klyce S D, Reidy J J, Insler M S
LSU Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans 70112.
Ophthalmology. 1990 Jun;97(6):734-44. doi: 10.1016/s0161-6420(90)32516-2.
Twenty-one eyes of 12 patients with contact lens-induced corneal warpage were followed prospectively using computer-assisted topographic analysis. Sixteen eyes had worn rigid contact lenses (13 eyes, polymethylmethacrylate; three eyes, gas-permeable), and five eyes had worn soft contact lenses. Initial corneal topographic patterns were characterized by the presence of central irregular astigmatism, loss of radial symmetry, and frequent reversal of the normal topographic pattern of progressive flattening of corneal contour from the center to the periphery. A correlation was noted between the initial corneal topography and the resting position of the contact lens on the cornea for nine of the 16 eyes with rigid contact lenses. Initial topography for each of these corneas showed relative flattening of the corneal contour underlying the resting position of a decentered contact lens. Superior-riding lenses produced a topography that simulated early keratoconus. After cessation of contact lens wear, 16 of 21 eyes had a change in corneal shape to a topography that was consistent with a normal pattern. Five corneas stabilized with an abnormal topographic pattern. A much longer time without contact lenses than had been previously reported, up to 5 months, was required for a return of a stable corneal topography in eyes with contact lens-induced corneal warpage caused by rigid lenses.
对12例因佩戴隐形眼镜导致角膜变形的患者的21只眼睛进行了前瞻性随访，采用计算机辅助地形图分析。16只眼睛佩戴过硬性隐形眼镜（13只眼睛佩戴聚甲基丙烯酸甲酯材质；3只眼睛佩戴透气材质），5只眼睛佩戴过软性隐形眼镜。初始角膜地形图特征为中央不规则散光、径向对称性丧失，以及角膜轮廓从中心到周边逐渐变平的正常地形图模式频繁反转。在16只佩戴硬性隐形眼镜的眼睛中，有9只眼睛的初始角膜地形图与隐形眼镜在角膜上的静止位置之间存在相关性。这些角膜中的每一只的初始地形图显示，偏心隐形眼镜静止位置下方的角膜轮廓相对变平。上位佩戴的镜片产生的地形图模拟了早期圆锥角膜。停止佩戴隐形眼镜后，21只眼睛中有16只眼睛的角膜形状发生了变化，变为与正常模式一致的地形图。5只角膜的地形图异常稳定。对于因硬性镜片导致隐形眼镜相关性角膜变形的眼睛，恢复稳定的角膜地形图需要比之前报道的长得多的无隐形眼镜时间，长达5个月。
