Guangdong Province Pharmaceutical Association, Guangzhou, China.
Med Sci Monit. 2013 Jun 7;19:438-43. doi: 10.12659/MSM.883935.
Different individuals have different degrees of neuroplasticity due to their different experiences. Neuroplasticity may play a role in individual differences among neuropsychiatric disease treatment efficacy. Since the nervous system monitors and coordinates internal organ function, neuroplasticity may be associated with other diseases. Cardiovascular disease (CVD) is associated with depression, which is a disorder of disrupted neuroplasticity. MicroRNA-132 (miR-132) has a roles in neuroplasticity and cardiovascular function. Thus, we hypothesize that miR-132 may play a role in coexistence of depression and CVD.
不同个体因其不同的经历而具有不同程度的神经可塑性。神经可塑性可能在神经精神疾病治疗效果的个体差异中发挥作用。由于神经系统监测和协调内部器官功能，神经可塑性可能与其他疾病有关。心血管疾病（CVD）与抑郁症有关，后者是一种神经可塑性紊乱的疾病。microRNA-132（miR-132）在神经可塑性和心血管功能中发挥作用。因此，我们假设 miR-132 可能在抑郁症和 CVD 的共存中发挥作用。
