College of Pharmacy-Pulido Center, The University of Arizona College of Pharmacy, 1295 N Martin P.O. Box 210202, Tucson, AZ, 85721-0202, USA.
Qual Life Res. 2014 Feb;23(1):129-34. doi: 10.1007/s11136-013-0445-2. Epub 2013 Jun 8.
Identify predictors of quality of life (QOL) in patients with any form of cardiac arrhythmia (CA).
Data from the Medical Panel Expenditure Survey were analyzed from 2004 to 2009. Patients aged ≥18 with any form of CA (identified via ICD-9-CM codes) were included. Primary outcomes included the physical and mental component scores (PCS and MCS) of the Short-Form 12 version 2 (SF-12) and EuroQoL-5D (EQ-5D) utility scores (US version). Patient demographics included insurance status, urban status, geographical region, federal poverty level, education, comorbidities, and disease-related risk factors of CA.
Approximately 5,750,440 individuals had CA. Non-Hispanic Whites had the highest SF-12 MCS (mean 50.9; p < 0.001 across racial groups) and utility scores (mean 0.76; p < 0.001 across racial groups). Patients with both private and public insurance had significantly higher PCS (p = 0.001) and MCS (p < 0.001) in comparison with patients only covered by public insurance. Patients on antiarrhythmic agents had higher SF-12 MCS (51.4 vs. 48.4; p < 0.001) compared to individuals not on antiarrhythmic agents.
Significantly lower QOL existed in specific subpopulations (e.g., patients with only public health insurance, racial/ethnic minorities, and those not exposed to antiarrhythmic agents) within the CA population.
确定任何类型心律失常(CA)患者生活质量(QOL)的预测因素。
分析了 2004 年至 2009 年期间医疗小组支出调查的数据。纳入年龄≥18 岁且患有任何类型 CA(通过 ICD-9-CM 代码确定)的患者。主要结局包括短期表单 12 版本 2(SF-12)的身体和精神成分评分(PCS 和 MCS)以及 EuroQoL-5D(EQ-5D)效用评分(US 版本)。患者人口统计学特征包括保险状况、城市状况、地理位置、联邦贫困水平、教育、合并症和 CA 的疾病相关危险因素。
约有 5750440 人患有 CA。非西班牙裔白人的 SF-12 MCS 最高(种族群体之间平均为 50.9;p<0.001),效用评分也最高(种族群体之间平均为 0.76;p<0.001)。与仅拥有公共保险的患者相比,同时拥有私人和公共保险的患者的 PCS 和 MCS 显著更高(p=0.001)。使用抗心律失常药物的患者的 SF-12 MCS 更高(51.4 比 48.4;p<0.001),与未使用抗心律失常药物的患者相比。
在 CA 人群中的特定亚群(例如,仅拥有公共医疗保险、少数民族和未使用抗心律失常药物的患者)中,QOL 明显较低。