Department of Obstetrics and Gynaecology, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
PLoS One. 2013 Jun 5;8(6):e62364. doi: 10.1371/journal.pone.0062364. Print 2013.
Caesarean delivery (CD) rates are commonly used as an indicator of quality in obstetric care and risk adjustment evaluation is recommended to assess inter-institutional variations. The aim of this study was to evaluate whether the Ten Group classification system (TGCS) can be used in case-mix adjustment.
Standardized data on 15,255 deliveries from 11 different regional centers were prospectively collected. Crude Risk Ratios of CDs were calculated for each center. Two multiple logistic regression models were herein considered by using: Model 1- maternal (age, Body Mass Index), obstetric variables (gestational age, fetal presentation, single or multiple, previous scar, parity, neonatal birth weight) and presence of risk factors; Model 2- TGCS either with or without maternal characteristics and presence of risk factors. Receiver Operating Characteristic (ROC) curves of the multivariate logistic regression analyses were used to assess the diagnostic accuracy of each model. The null hypothesis that Areas under ROC Curve (AUC) were not different from each other was verified with a Chi Square test and post hoc pairwise comparisons by using a Bonferroni correction.
Crude evaluation of CD rates showed all centers had significantly higher Risk Ratios than the referent. Both multiple logistic regression models reduced these variations. However the two methods ranked institutions differently: model 1 and model 2 (adjusted for TGCS) identified respectively nine and eight centers with significantly higher CD rates than the referent with slightly different AUCs (0.8758 and 0.8929 respectively). In the adjusted model for TGCS and maternal characteristics/presence of risk factors, three centers had CD rates similar to the referent with the best AUC (0.9024).
The TGCS might be considered as a reliable variable to adjust CD rates. The addition of maternal characteristics and risk factors to TGCS substantially increase the predictive discrimination of the risk adjusted model.
剖宫产率通常被用作产科护理质量的指标,建议进行风险调整评估,以评估机构间的差异。本研究旨在评估十组分类系统(TGCS)是否可用于病例组合调整。
前瞻性收集了来自 11 个不同区域中心的 15255 例分娩的标准化数据。为每个中心计算了剖宫产的粗风险比。在此考虑了两种多因素逻辑回归模型:模型 1- 产妇(年龄、体重指数)、产科变量(胎龄、胎儿方位、单胎或多胎、既往瘢痕、产次、新生儿出生体重)和危险因素的存在;模型 2- 有无 TGCS 和产妇特征及危险因素的存在。使用多变量逻辑回归分析的接收者操作特征(ROC)曲线评估每个模型的诊断准确性。使用卡方检验和事后两两比较(Bonferroni 校正)验证 AUC 无差异的零假设。
剖宫产率的初步评估显示,所有中心的风险比均明显高于参考值。两种多因素逻辑回归模型均降低了这些差异。然而,这两种方法对机构的排名不同:模型 1 和模型 2(调整 TGCS)分别确定了 9 个和 8 个中心的剖宫产率明显高于参考值,AUC 略有不同(分别为 0.8758 和 0.8929)。在调整了 TGCS 和产妇特征/危险因素的模型中,有 3 个中心的剖宫产率与参考值相似,AUC 最高(0.9024)。
TGCS 可作为调整剖宫产率的可靠变量。在 TGCS 中加入产妇特征和危险因素可显著提高风险调整模型的预测区分度。