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含无刺散沫花(指甲花)叶提取物的抗菌聚乙烯醇和聚环氧乙烷纳米纤维的制备

Preparation of antibacterial PVA and PEO nanofibers containing Lawsonia Inermis (henna) leaf extracts.

作者信息

Avci H, Monticello R, Kotek R

机构信息

a College of Textiles, Textile Engineering Chemistry and Science, North Carolina State University , Raleigh , NC , 27695-8301 , USA.

出版信息

J Biomater Sci Polym Ed. 2013;24(16):1815-30. doi: 10.1080/09205063.2013.804758. Epub 2013 Jun 13.

DOI:10.1080/09205063.2013.804758
PMID:23758488
Abstract

Concerns about health issues and environmental pollution stimulate research to find new health and hygiene related products with healing properties and minimum negative effect on the environment. Development of new, natural antibacterial agents has become one of the most important research areas to combat some pathogens such as Gram- positive and Gram-negative bacteria, fungi, algae, yeast, and some microorganisms which cause serious human infections. Lawsonia Inermis (henna) leaf extracts for preparation of antibacterial poly(ethylene oxide) (PEO) and poly(vinyl alcohol) (PVA) nanofibers via electrospinning technique were investigated. PEO and PVA based electrospun fibers containing henna extract were verified by the appearance of FTIR peaks corresponding to the pure extract. Our study demonstrates that 2.793 wt.% Li in PVA and PEO based solutions showed bactericidal effects against Staphylococcus aureus and bacteriostatic action to Escherichia coli. Concentrations of henna leaf extract strongly impacted antibacterial activities against both bacteria. Henna leaves have a great potential to be used as a source of a potent eco-friendly antimicrobial agent.

摘要

对健康问题和环境污染的担忧促使人们开展研究,以寻找具有治疗特性且对环境负面影响最小的新型健康与卫生相关产品。开发新型天然抗菌剂已成为对抗某些病原体(如革兰氏阳性菌和革兰氏阴性菌、真菌、藻类、酵母以及一些导致严重人类感染的微生物)的最重要研究领域之一。研究了通过静电纺丝技术制备含抗菌聚环氧乙烷(PEO)和聚乙烯醇(PVA)纳米纤维的散沫花(指甲花)叶提取物。含指甲花叶提取物的基于PEO和PVA的电纺纤维通过对应纯提取物的FTIR峰的出现得到验证。我们的研究表明,在基于PVA和PEO的溶液中2.793 wt.%的指甲花显示出对金黄色葡萄球菌的杀菌作用以及对大肠杆菌的抑菌作用。指甲花叶提取物的浓度对两种细菌的抗菌活性有强烈影响。指甲花叶极有潜力用作强效环保抗菌剂的来源。

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