Kazmierczak M, Mather M, Ciancio S, Fischman S, Cancro L
Clin Prev Dent. 1990 Apr-May;12(1):13-7.
One hundred and eighty-seven patients participated in a six-month study to evaluate the calculus-inhibiting effect of a zinc citrate dentifrice compared to Crest Tartar Control and a placebo, Crest Regular. The findings demonstrate a statistically significant calculus prevention benefit over Crest Regular for both Crest Tartar Control and a 2% zinc citrate/silica product. Compared to the control, the zinc citrate product reduced calculus formation by 32.3%, and Crest Tartar Control reduced it by 21.4%. These findings also demonstrate no statistically significant difference in stain or soft tissue status among the three dentifrices. All products were found to be safe to oral tissues and acceptable for taste.
187名患者参与了一项为期六个月的研究，以评估柠檬酸锌牙膏与佳洁士防垢牙膏和安慰剂佳洁士普通牙膏相比的防结石效果。研究结果表明，与佳洁士普通牙膏相比，佳洁士防垢牙膏和含2%柠檬酸锌/二氧化硅的产品在预防牙结石方面具有统计学上的显著益处。与对照组相比，柠檬酸锌产品使牙结石形成减少了32.3%，佳洁士防垢牙膏使牙结石形成减少了21.4%。这些研究结果还表明，三种牙膏在污渍或软组织状况方面没有统计学上的显著差异。所有产品均被发现对口腔组织安全且味道可接受。
