Papasouliotis K, Tennant K V, Dodkin S, Mason J
Diagnostic Laboratories, Langford Veterinary Services, University of Bristol, Langford, Bristol BS40 5DU, UK ; School of Veterinary Science, University of Bristol, Langford, Bristol BS40 5DU, UK.
ISRN Vet Sci. 2012 Sep 27;2012:475419. doi: 10.5402/2012/475419. Print 2012.
Falcor 350 is a wet-reagent biochemistry analyser that is available for in-house use. The aim of this study was to compare the results produced by this analyser with those obtained by the KoneLab 30i that served as the reference instrument. Blood samples from 60 clinical cases were analysed for urea, creatinine, total proteins, albumin, creatine kinase, aspartate aminotransferase, alkaline phosphatase, total bilirubin, total calcium, phosphate, sodium, and potassium using both instruments. Good to excellent correlations (r s value) value) were identified for creatinine (0.88), total proteins (0.92), albumin (0.93), creatine kinase (0.98), aspartate aminotransferase (0.98), alkaline phosphatase (0.94), total bilirubin (0.98), phosphate (0.95), and potassium (0.97). The correlations for total calcium (0.71), sodium (0.68), and urea (0.64) were fair. For albumin, aspartate aminotransferase, creatine kinase, phosphate, potassium, total bilirubin, creatinine, and total proteins, the two instruments produce values that are closely related to each other and are sufficiently similar to allow them to be used interchangeably without the need for additional correction factor computations. Because of differences in the methodologies, the Falcor results for alkaline phosphatase, total calcium, and sodium cannot be used interchangeably and should be interpreted using reference intervals established from the Falcor analyser.
Falcor 350是一款可供内部使用的湿试剂生化分析仪。本研究的目的是将该分析仪产生的结果与作为参考仪器的KoneLab 30i所获得的结果进行比较。使用这两种仪器对60例临床病例的血样进行尿素、肌酐、总蛋白、白蛋白、肌酸激酶、天冬氨酸氨基转移酶、碱性磷酸酶、总胆红素、总钙、磷酸盐、钠和钾的分析。肌酐(0.88)、总蛋白(0.92)、白蛋白(0.93)、肌酸激酶(0.98)、天冬氨酸氨基转移酶(0.98)、碱性磷酸酶(0.94)、总胆红素(0.98)、磷酸盐(0.95)和钾(0.97)的相关性良好至极佳。总钙(0.71)、钠(0.68)和尿素(0.64)的相关性一般。对于白蛋白、天冬氨酸氨基转移酶、肌酸激酶、磷酸盐、钾、总胆红素、肌酐和总蛋白,这两种仪器产生的值彼此密切相关且足够相似,无需额外计算校正因子即可互换使用。由于方法学上的差异,Falcor分析仪检测碱性磷酸酶、总钙和钠的结果不能互换使用,应使用Falcor分析仪建立的参考区间进行解释。