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色素沉着性病毒相关结膜癌

Pigmented viral-associated conjunctival carcinoma.

作者信息

Charles Norman C, Marr Brian P, Stenson Susan M, Mittal Khushbakhat R

机构信息

Department of Ophthalmology, New York University Medical Center, 550 First Avenue, New York, NY 10016, USA ; Department of Pathology, New York University Medical Center, 550 First Avenue, New York, NY 10016, USA.

出版信息

Case Rep Ophthalmol Med. 2013;2013:783104. doi: 10.1155/2013/783104. Epub 2013 May 9.

DOI:10.1155/2013/783104
PMID:23762697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3665221/
Abstract

A 54-year-old African-American woman developed a pigmented papillary squamous cell carcinoma in the palpebral and bulbar conjunctiva of the right eye in areas that received no sun exposure. In situ hybridization performed on the tumor showed human papilloma virus 16. The left eye showed a pedunculated nonpigmented conjunctival dysplasia. The tumors were extirpated by cryosurgery and topical interferon alfa 2b in the right eye and simple surgical excision in the left eye.

摘要

一名54岁的非裔美国女性,在右眼睑结膜和球结膜未受阳光照射的区域发生了色素性乳头状鳞状细胞癌。对肿瘤进行的原位杂交显示人乳头瘤病毒16型。左眼表现为带蒂的无色素结膜发育异常。右眼的肿瘤通过冷冻手术和局部注射干扰素α 2b切除,左眼的肿瘤通过简单手术切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9b5/3665221/c4193529519d/CRIM.OPHMED2013-783104.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9b5/3665221/0aaaed54e6b3/CRIM.OPHMED2013-783104.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9b5/3665221/78a7154f6d15/CRIM.OPHMED2013-783104.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9b5/3665221/c4193529519d/CRIM.OPHMED2013-783104.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9b5/3665221/0aaaed54e6b3/CRIM.OPHMED2013-783104.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9b5/3665221/78a7154f6d15/CRIM.OPHMED2013-783104.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9b5/3665221/c4193529519d/CRIM.OPHMED2013-783104.003.jpg

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本文引用的文献

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No evidence for a pathogenic role of human papillomavirus infection in ocular surface squamous neoplasia in Germany.在德国,没有证据表明人乳头瘤病毒感染在眼表鳞状上皮肿瘤中起致病作用。
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