Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599, USA.
J Acquir Immune Defic Syndr. 2013 Jul;63 Suppl 2(0 2):S155-60. doi: 10.1097/QAI.0b013e31829871fb.
To review the current state of knowledge on the prevention of sexual transmission of HIV in adolescents and to highlight the existing gaps and priority areas for future research.
A disproportionate burden of HIV infections falls on adolescents, a developmental stage marked by unique neural, biological, and social transition. Successful interventions are critical to prevent the spread of HIV in this vulnerable population.
We summarized the current state of research on HIV prevention in adolescents by providing examples of successful interventions and best practices, and highlighting current research gaps.
Adolescent interventions fall into 3 main categories: biomedical, behavioral, and structural. The majority of current research has focused on individual behavior change, whereas promising biomedical and structural interventions have been largely understudied in adolescents. Combination prevention interventions may be particularly valuable to this group.
Adolescents have unique needs with respect to HIV prevention, and, thus, interventions should be designed to most effectively reach out to this population with information and services that will be relevant to them.
回顾青少年艾滋病性传播预防的现有知识状况，并强调未来研究的现有差距和重点领域。
艾滋病毒感染的负担不成比例地落在青少年身上，这是一个以独特的神经、生物和社会过渡为标志的发展阶段。成功的干预措施对于防止这一脆弱人群中艾滋病毒的传播至关重要。
我们通过提供成功干预措施和最佳实践的例子，总结了青少年艾滋病毒预防研究的现状，并强调了当前的研究差距。
青少年干预措施分为 3 类：生物医学、行为和结构。目前大多数研究都集中在个体行为改变上，而有前途的生物医学和结构干预措施在青少年中研究甚少。组合预防干预措施可能对这一群体特别有价值。
青少年在艾滋病预防方面有独特的需求，因此，干预措施的设计应旨在最有效地向这一人群提供与他们相关的信息和服务。
