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主要的系统评价能影响实践模式吗?会阴切开术趋势的案例研究。

Can major systematic reviews influence practice patterns? A case study of episiotomy trends.

机构信息

Graduate School of Business and Public Policy, Naval Postgraduate School, 555 Dyer Road, Code GB, Monterey, CA, 93943, USA,

出版信息

Arch Gynecol Obstet. 2013 Dec;288(6):1285-93. doi: 10.1007/s00404-013-2904-y. Epub 2013 Jun 14.

Abstract

PURPOSE

Episiotomy is one of the most commonly performed procedures among women of childbearing age in the United States. In 2005, a major systematic review conducted by Hartmann and colleagues recommended against routine use of episiotomy and was widely covered in the media. We assessed the impact of the Hartman et al. study on episiotomy trend.

METHODS

Based on 100% hospital discharge data from eight states in 2003-2008, we used interrupted time series regression models to estimate the impact of the Hartman et al. review on episiotomy rates. We used mixed-effects regression models to assess whether interhospital variation was reduced over time.

RESULTS

After controlling for underlying trend, episiotomy rates dropped by 1.4 percentage points after Hartman et al. publication (p < 0.01 for spontaneous delivery; p < 0.1 for operative delivery). The publication has smaller effect on government hospitals as compared to private hospitals. Mixed effects models estimated negative correlation between cross-time and cross-hospital variations in episiotomy rates, indicating reduced cross-hospital variation over time.

CONCLUSIONS

Our results suggested that there has been a gradual decline in episiotomy rates over the period 2003-2008, and that synthesis of evidence showing harms from routine episiotomy had limited impact on practice patterns in the case of episiotomy. The experience of episiotomy illustrates the challenge of using comparative effectiveness and evidenced-based medicine to reduce use of unnecessary procedures.

摘要

目的

会阴切开术是美国育龄妇女中最常见的手术之一。2005 年,Hartmann 及其同事进行的一项主要系统评价建议反对常规使用会阴切开术,并在媒体上广泛报道。我们评估了 Hartman 等人的研究对会阴切开术趋势的影响。

方法

基于 2003-2008 年八个州的 100%住院数据,我们使用中断时间序列回归模型来估计 Hartman 等人的综述对会阴切开术率的影响。我们使用混合效应回归模型来评估医院间的差异是否随时间减少。

结果

在控制潜在趋势后,Hartman 等人发表后,会阴切开术率下降了 1.4 个百分点(自然分娩时 p<0.01;剖宫产时 p<0.1)。与私立医院相比,该研究对公立医院的影响较小。混合效应模型估计会阴切开术率的跨时间和跨医院变化之间存在负相关,表明随着时间的推移,医院间的差异有所减少。

结论

我们的研究结果表明,2003-2008 年期间会阴切开术率逐渐下降,证据综合表明常规会阴切开术的危害对会阴切开术的实践模式影响有限。会阴切开术的经验说明了利用循证医学和比较有效性来减少不必要手术的使用所面临的挑战。

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