Arq Bras Cardiol. 2013 Aug;101(2):169-75. doi: 10.5935/abc.20130127. Epub 2013 Jun 14.
EnSiteNavx electroanatomic mapping system is widely used in radiofrequency (RF) atrial fibrillation ablation, helping the creation of linear lesions. However, the correspondence of the virtual line created by EnSite with the pathological lesion has not yet been evaluated.
to assess the continuousness of Ensite-guided virtual lines in a swine model.
we performed RF ablation linear lesions (8mm and irrigated catheters tips) in both atria of 14 pigs (35 Kg) guided by the EnSite. The animals were sacrificed 14 days post-ablation for macroscopic and histological analysis.
a total of 23 lines in the right atrium and 21 lines in the left atrium were created in 14 animals. The medium power, impedance and temperature applications were 56 W, 54 ºC and 231 Ω for the 8mm tip, and 39 W, 37 ºC, 194 Ω for the irrigated tip catheter, respectively. All (100%) lines were identified on the epicardial and endocardial surfaces, denoting transmurality. At macroscopic examination, lesions were extensive and pale, continuous, with 3.61 cm long and 0.71 cm deep. The transmurality of the lesions was confirmed by microscopy. There was a correlation in the location of the lines at the virtual map and the anatomical lesions in 21 of 23 (91.3%) of the right atrium and 19/21 (90.4%) of the left atrium.
In this model, the lines created in the virtual map by EnSiteNavX system correspond to continuous transmural linear lesions in anatomical specimen, suggesting that this method is suitable for linear ablation of atrial fibrillation.
EnSiteNavx 电生理标测系统广泛应用于射频（RF）房颤消融术，有助于线性消融病灶的形成。然而，EnSite 所创建的虚拟线与病理病灶之间的对应关系尚未得到评估。
评估 EnSite 引导的虚拟线在猪模型中的连续性。
我们在 14 只（35 公斤）猪的左右心房中使用 EnSite 进行 RF 消融线性消融（8mm 和灌流导管尖端）。在消融后 14 天处死动物，进行大体和组织学分析。
在 14 只动物中，共在右心房创建了 23 条线，在左心房创建了 21 条线。8mm 尖端的平均功率、阻抗和温度应用分别为 56W、54°C 和 231Ω，而灌流导管尖端的平均功率、阻抗和温度应用分别为 39W、37°C 和 194Ω。所有（100%）的线在心外膜和心内膜表面都可以识别，表明透壁性。大体检查时，病变广泛且苍白，连续，长 3.61cm，深 0.71cm。显微镜检查证实了病变的透壁性。在右心房的 23 条线中的 21 条（91.3%）和左心房的 21 条线中的 19 条（90.4%），虚拟地图上的线的位置与解剖学病变的位置相吻合。
在该模型中，EnSiteNavX 系统在虚拟地图上创建的线与解剖标本中的连续透壁线性消融病灶相对应，表明该方法适用于心房颤动的线性消融。
