• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

恢复不可见和被遗弃的试验:呼吁人们公布研究结果。

Restoring invisible and abandoned trials: a call for people to publish the findings.

机构信息

Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

BMJ. 2013 Jun 13;346:f2865. doi: 10.1136/bmj.f2865.

DOI:10.1136/bmj.f2865
PMID:23766480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3685516/
Abstract

Unpublished and misreported studies make it difficult to determine the true value of a treatment. call for sponsors and investigators of abandoned studies to publish (or republish) and propose a system for independent publishing if sponsors fail to respond

摘要

未发表和误报的研究使得确定治疗的真正价值变得困难。呼吁放弃研究的赞助商和研究者发表(或重新发表)研究结果,如果赞助商未能回应,则建议建立独立发表的系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d89/4790819/758094fbd2b7/dosp007749.f1_default.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d89/4790819/758094fbd2b7/dosp007749.f1_default.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d89/4790819/758094fbd2b7/dosp007749.f1_default.jpg

相似文献

1
Restoring invisible and abandoned trials: a call for people to publish the findings.恢复不可见和被遗弃的试验:呼吁人们公布研究结果。
BMJ. 2013 Jun 13;346:f2865. doi: 10.1136/bmj.f2865.
2
Independent researchers should have right to publish trial results if original researchers don't, campaigners say.活动人士表示,如果原始研究人员不公布试验结果,独立研究人员应有权公布。
BMJ. 2013 Jun 13;346:f3857. doi: 10.1136/bmj.f3857.
3
Who is responsible for publishing the results of old trials?谁负责公布旧试验的结果?
BMJ. 2013 Dec 10;347:f7199. doi: 10.1136/bmj.f7199.
4
ACCE, pharmacogenomics, and stopping clinical trials: time to extend the CONSORT statement?ACCE、药物基因组学与临床试验终止:是时候扩展CONSORT声明了吗?
Am J Bioeth. 2011 Mar;11(3):11-3. doi: 10.1080/15265161.2010.546477.
5
Trial Discontinuation and Publication Outcome: Resource Wastage in Low Back Pain Research.试验终止与发表结果:腰痛研究中的资源浪费
Spine (Phila Pa 1976). 2023 Jul 1;48(13):E219. doi: 10.1097/BRS.0000000000004524. Epub 2022 Nov 2.
6
Restoring the integrity of the clinical trial evidence base.恢复临床试验证据基础的完整性。
BMJ. 2013 Jun 13;346:f3601. doi: 10.1136/bmj.f3601.
7
Publishing "Invisible" and "Abandoned" clinical trials: a commitment for CTS.公布“隐形”和“被弃用”的临床试验:CTS的一项承诺。
Clin Transl Sci. 2013 Aug;6(4):251-3. doi: 10.1111/cts.12087.
8
Randomized trials addressing a similar question are commonly published after a trial stopped early for benefit.针对类似问题的随机试验通常在提前因获益而停止后发布。
J Clin Epidemiol. 2017 Feb;82:12-19. doi: 10.1016/j.jclinepi.2016.10.006. Epub 2016 Nov 8.
9
Nonpublication and discontinuation of randomised controlled trials in newborns.新生儿随机对照试验的未发表及中止情况。
Acta Paediatr. 2017 Dec;106(12):1940-1944. doi: 10.1111/apa.14062. Epub 2017 Sep 20.
10
Early Termination of Randomized Clinical Trials in Orthopaedics.骨科随机临床试验的早期终止
Surg Technol Int. 2017 Feb 7;30:290-294.

引用本文的文献

1
Reporting of interventional clinical trial results in an academic center: a survey of completed studies.学术中心介入临床试验结果报告:已完成研究调查。
BMC Med Res Methodol. 2024 Apr 22;24(1):93. doi: 10.1186/s12874-024-02221-6.
2
Lifestyle Coaching May Be an Effective Treatment for Schizophrenia.生活方式指导可能是治疗精神分裂症的有效方法。
Am J Lifestyle Med. 2022 Dec 1;18(2):156-161. doi: 10.1177/15598276221142307. eCollection 2024 Mar-Apr.
3
Treatment guesses in the Treatment for Adolescents with Depression Study: Accuracy, unblinding and influence on outcomes.

本文引用的文献

1
The first 2 years of the European Medicines Agency's policy on access to documents: secret no longer.欧洲药品管理局文件获取政策的头两年:不再保密。
JAMA Intern Med. 2013 Mar 11;173(5):380-2. doi: 10.1001/jamainternmed.2013.3838.
2
Clinical study reports of randomised controlled trials: an exploratory review of previously confidential industry reports.随机对照试验的临床研究报告:先前保密的行业报告的探索性综述。
BMJ Open. 2013 Feb 26;3(2). doi: 10.1136/bmjopen-2012-002496. Print 2013.
3
Restoring confidence in the pharmaceutical industry.
治疗猜测在青少年抑郁症研究中的作用:准确性、揭盲和对结果的影响。
Aust N Z J Psychiatry. 2024 Apr;58(4):355-364. doi: 10.1177/00048674231218623. Epub 2023 Dec 21.
4
What are the treatment remission, response and extent of improvement rates after up to four trials of antidepressant therapies in real-world depressed patients? A reanalysis of the STAR*D study's patient-level data with fidelity to the original research protocol.在真实世界的抑郁症患者中,经过多达四次抗抑郁治疗试验后,治疗缓解率、反应率和改善程度的比率是多少?对 STAR*D 研究患者水平数据的忠实重新分析,符合原始研究方案。
BMJ Open. 2023 Jul 25;13(7):e063095. doi: 10.1136/bmjopen-2022-063095.
5
Need for Multidimensional and Multidisciplinary Management of Depressed Preadolescents and Adolescents: A Review of Randomized Controlled Trials on Oral Supplementations (Omega-3, Fish Oil, Vitamin D).需要对抑郁的青春期前和青春期儿童进行多维和多学科管理:口服补充剂(欧米伽 3、鱼油、维生素 D)的随机对照试验综述
Nutrients. 2023 May 15;15(10):2306. doi: 10.3390/nu15102306.
6
Restoring Study PRGF: a randomized clinical trial on plasma rich in growth factors for knee osteoarthritis.恢复研究 PRGF:富含生长因子的富血小板血浆治疗膝关节骨关节炎的随机临床试验。
Trials. 2023 Jan 18;24(1):37. doi: 10.1186/s13063-022-07049-3.
7
Restoring mortality data in the FOURIER cardiovascular outcomes trial of evolocumab in patients with cardiovascular disease: a reanalysis based on regulatory data.在 FOURIER 心血管结局试验中恢复依洛尤单抗治疗心血管疾病患者的死亡率数据:基于监管数据的重新分析。
BMJ Open. 2022 Dec 30;12(12):e060172. doi: 10.1136/bmjopen-2021-060172.
8
Influenza polymerase inhibitor resistance: Assessment of the current state of the art - A report of the isirv Antiviral group.流感聚合酶抑制剂耐药性:现状评估——国际抗病毒研究学会(isirv)抗病毒小组报告。
Antiviral Res. 2021 Oct;194:105158. doi: 10.1016/j.antiviral.2021.105158. Epub 2021 Aug 4.
9
Restoring invisible and abandoned trials of gabapentin for neuropathic pain: a clinical and methodological investigation.重新评估加巴喷丁治疗神经病理性疼痛的未发表和被遗弃试验:一项临床和方法学调查。
BMJ Open. 2021 Jun 30;11(6):e047785. doi: 10.1136/bmjopen-2020-047785.
10
Social media attention and citations of published outputs from re-use of clinical trial data: a matched comparison with articles published in the same journals.社交媒体关注度与临床研究数据再利用发表成果的引用情况:与同一期刊发表文章的匹配比较
BMC Med Res Methodol. 2021 Jun 6;21(1):119. doi: 10.1186/s12874-021-01311-z.
恢复对制药行业的信心。
JAMA. 2013 Feb 13;309(6):607-9. doi: 10.1001/jama.2013.58.
4
Differences in reporting of analyses in internal company documents versus published trial reports: comparisons in industry-sponsored trials in off-label uses of gabapentin.公司内部文件与已发表试验报告中分析结果报告的差异:加巴喷丁未上市用途的行业资助试验中的比较。
PLoS Med. 2013;10(1):e1001378. doi: 10.1371/journal.pmed.1001378. Epub 2013 Jan 29.
5
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials.SPIRIT 2013 解释和说明:临床试验方案指南。
BMJ. 2013 Jan 8;346:e7586. doi: 10.1136/bmj.e7586.
6
SPIRIT 2013 statement: defining standard protocol items for clinical trials.SPIRIT 2013 声明:定义临床试验的标准议定书项目。
Ann Intern Med. 2013 Feb 5;158(3):200-7. doi: 10.7326/0003-4819-158-3-201302050-00583.
7
Ten recommendations for closing the credibility gap in reporting industry-sponsored clinical research: a joint journal and pharmaceutical industry perspective.缩小行业资助临床研究报告中可信度差距的十条建议:期刊与制药行业联合视角
Mayo Clin Proc. 2012 May;87(5):424-9. doi: 10.1016/j.mayocp.2012.02.009.
8
Characteristics of clinical trials registered in ClinicalTrials.gov, 2007-2010.2007-2010 年 ClinicalTrials.gov 注册临床试验的特征。
JAMA. 2012 May 2;307(17):1838-47. doi: 10.1001/jama.2012.3424.
9
Open clinical trial data for all? A view from regulators.公开所有临床试验数据?监管者的观点。
PLoS Med. 2012;9(4):e1001202. doi: 10.1371/journal.pmed.1001202. Epub 2012 Apr 10.
10
The imperative to share clinical study reports: recommendations from the Tamiflu experience.分享临床研究报告的必要性:来自达菲经验的建议。
PLoS Med. 2012;9(4):e1001201. doi: 10.1371/journal.pmed.1001201. Epub 2012 Apr 10.