Nikawa Y, Kikuchi M, Terakawa T, Matsuda T
Department of Electrical Engineering, National Defense Academy, Yokosuka, Japan.
Int J Hyperthermia. 1990 May-Jun;6(3):671-84. doi: 10.3109/02656739009140963.
To attain deep and localized heating for hyperthermic treatment of cancers, metal plate lens applicators that can converge microwave electromagnetic (EM) energy in the lossy medium such as human muscle with a computer-controlled heating system have been developed. This paper describes a system operating at 430 MHz. Results of an electric-field distribution calculation and a heating experiment made on a saline solution phantom show that the maximum heating depth is over 60 mm using the lens applicator, which is twice as deep as that obtained with a conventional waveguide applicator. The experimental results agree well with the theoretical ones. A computer-controlled heating system has been developed using the applicator. Experimental results show that fluctuations in temperature at locations in the heating region of the saline phantom were maintained within +/- 0.3 degrees C of the present temperatures. These results indicate that the system can be used for the clinical hyperthermia treatment of cancer.
为了实现癌症热疗所需的深部和局部加热，人们已经开发出金属板透镜施加器，它可以通过计算机控制的加热系统在人体肌肉等有损介质中汇聚微波电磁（EM）能量。本文介绍了一种工作在430MHz的系统。在盐溶液模型上进行的电场分布计算和加热实验结果表明，使用透镜施加器时最大加热深度超过60mm，这是传统波导施加器所获加热深度的两倍。实验结果与理论结果吻合良好。利用该施加器开发了一种计算机控制的加热系统。实验结果表明，盐溶液模型加热区域内各位置的温度波动保持在当前温度的±0.3℃以内。这些结果表明该系统可用于癌症的临床热疗。
