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用于治疗鼻咽癌和宫颈癌的腔内热疗施源器。

Intracavitary hyperthermia applicators for treating nasopharyngeal and cervical cancers.

作者信息

Zhong Q R, Chou C K, McDougall J A, Chan K W, Luk K H

机构信息

Department of Radiation Oncology, Tumor Hospital of Sun Yat-Sen University of Medical Sciences, Guangzhou, China.

出版信息

Int J Hyperthermia. 1990 Nov-Dec;6(6):997-1004. doi: 10.3109/02656739009140982.

Abstract

Many intracavitary microwave applicators have been designed to heat tissues along the side of an antenna. For tumours in nearly closed-end cavities such as the nasopharynx and cervix, heating near the tip of the applicators is necessary for effective treatment. A nasopharyngeal applicator made of Micro Coax UT-250A and a cervical applicator made of RG-9/U cables were designed to provide heating at the tip. Return losses of 8-12 dB were obtained at 915 MHz by varying the size of two metal sleeves and adjusting the distance between these sleeves and the reflectors at the applicator tips. Heating patterns were evaluated on a muscle phantom with a thermograph. At 915 MHz, maximum heating rates of 1.3 and 0.85 degrees C/W-min, respectively, were observed near the tip of the nasopharyngeal applicator and at its first sleeve opening. When operated at 915 MHz the cervical applicator has a maximum heating rate of 0.25 degrees C/W-min at the tip. Clinically, both applicators require a maximum power of 30 W to provide effective heating. This makes it possible to provide intracavitary hyperthermia at rural hospitals and small clinics with a small portable system.

摘要

许多腔内微波施热器被设计用于沿天线侧面加热组织。对于如鼻咽和宫颈等近封闭腔体内的肿瘤,为实现有效治疗,在施热器尖端附近进行加热是必要的。一款由Micro Coax UT - 250A制成的鼻咽施热器和一款由RG - 9/U电缆制成的宫颈施热器被设计用于在尖端提供加热。通过改变两个金属套筒的尺寸并调整这些套筒与施热器尖端反射器之间的距离,在915 MHz时获得了8 - 12 dB的回波损耗。使用热成像仪在肌肉模型上评估加热模式。在915 MHz时,在鼻咽施热器尖端及其第一个套筒开口处分别观察到最大加热速率为1.3和0.85摄氏度/瓦·分钟。当在915 MHz运行时,宫颈施热器在尖端的最大加热速率为0.25摄氏度/瓦·分钟。临床上,两款施热器都需要30 W的最大功率来提供有效加热。这使得使用小型便携式系统在农村医院和小型诊所进行腔内热疗成为可能。

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