Institute of Biology and Ecology, Faculty of Science, P. J. Šafárik University, Mánesova 23, SK-04001 Košice, Slovak Republic.
Food Chem. 2013 Nov 1;141(1):54-9. doi: 10.1016/j.foodchem.2013.03.004. Epub 2013 Mar 14.
The identity and quantity of coumarin-like compounds in leaves and anthodia of Matricaria chamomilla L. were studied by LC-DAD and NMR. So far, two monosubstituted coumarins, herniarin and umbelliferone, and two herniarin precursors were identified therein. In this paper, two other coumarin glycosides and one aglycone were confirmed. Skimmin (umbelliferone-7-O-β-d-glucoside), daphnin (daphnetin-7-O-β-d-glucoside) and daphnetin (7,8-dihydroxycoumarin) were found for the first time in diploid and tetraploid leaves and anthodia of M. chamomilla L. Daphnetin is known as a strong sensitizer, so this compound and its glycosidic derivative can contribute to the allergic potential of chamomile. Commercial chamomile preparations were tested for their presence.
采用 LC-DAD 和 NMR 法研究了母菊属植物叶和花蕾中香豆素类化合物的种类和含量。迄今为止，已从中鉴定出两种单取代香豆素，即茴芹香豆素和伞形酮，以及两种茴芹香豆素前体。在本研究中，还证实了另外两种香豆素糖苷和一种苷元。在二倍体和四倍体母菊属植物叶和花蕾中首次发现了 skimmin（伞形酮-7-O-β-d-葡萄糖苷）、daphnin（瑞香素-7-O-β-d-葡萄糖苷）和 daphnetin（7,8-二羟基香豆素）。瑞香素是一种很强的敏化剂，因此，该化合物及其糖苷衍生物可能有助于增加母菊的过敏潜力。对市售的母菊制剂进行了检测。
