Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Conn, USA.
Can J Ophthalmol. 2013 Jun;48(3):141-5. doi: 10.1016/j.jcjo.2013.02.003.
Given that glaucoma is a disease of the central nervous system, there must be greater emphasis and focus on developing intraocular pressure-independent therapies. In addition, scientific research investigating the role of sustained drug delivery is critical for advancing the field. Exciting innovation will require close collaboration and full integration of clinical and basic research efforts. Thus, translational research advances in neuroprotection may lead to future development of truly revolutionary therapies for glaucoma (e.g., neuroregeneration).
鉴于青光眼是一种中枢神经系统疾病,因此必须更加重视和专注于开发眼压非依赖性疗法。此外,科学研究调查持续药物输送的作用对于推动该领域的发展至关重要。令人兴奋的创新将需要密切合作和充分整合临床和基础研究工作。因此,神经保护的转化研究进展可能会为青光眼(例如神经再生)的真正革命性疗法的未来发展铺平道路。