年龄相关性黄斑变性：管理与诊断的进展
Age-Related Macular Degeneration: Advances in Management and Diagnosis.
作者信息
Yonekawa Yoshihiro, Miller Joan W, Kim Ivana K
机构信息
Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.
出版信息
J Clin Med. 2015 Feb 12;4(2):343-59. doi: 10.3390/jcm4020343.
Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in older populations in industrialized nations. AMD is a late-onset deterioration of photoreceptors and retinal pigment epithelium in the central retina caused by various environmental and genetic factors. Great strides in our understanding of AMD pathogenesis have been made in the past several decades, which have translated into revolutionary therapeutic agents in recent years. In this review, we describe the clinical and pathologic features of AMD and present an overview of current diagnosis and treatment strategies.
年龄相关性黄斑变性（AMD）是工业化国家老年人群不可逆视力损害的最常见原因。AMD是由多种环境和遗传因素导致的中央视网膜光感受器和视网膜色素上皮的迟发性退变。在过去几十年里，我们对AMD发病机制的理解取得了巨大进展，近年来已转化为具有革命性的治疗药物。在本综述中，我们描述了AMD的临床和病理特征，并概述了当前的诊断和治疗策略。
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