School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, Canada.
Arch Phys Med Rehabil. 2013 Sep;94(9):1829-1836.e7. doi: 10.1016/j.apmr.2013.05.015. Epub 2013 Jun 11.
Most adults with multiple sclerosis (MS) are physically inactive. Physical activity guidelines are an important tool for exercise prescription, promotion, and monitoring. This article describes the application of international standards for guideline development in the creation of evidence-based physical activity guidelines for people with MS. The development process was informed by the Appraisal of Guidelines Research and Evaluation II instrument. The evidence base for the guidelines consisted of a systematic review of research examining the effects of exercise on fitness, fatigue, mobility, and health-related quality of life among people with MS. A multidisciplinary consensus panel deliberated the evidence and generated the guidelines and a preamble. Expert and stakeholder reviews of the materials led to refinement of the wording of both components of the guidelines. The resulting guidelines state that to achieve important fitness benefits, adults with MS who have mild to moderate disability need at least 30 minutes of moderate intensity aerobic activity 2 times per week and strength training exercises for major muscle groups 2 times per week. Meeting these guidelines may also reduce fatigue, improve mobility, and enhance elements of health-related quality of life. People with MS and health professionals are encouraged to adopt these rigorously developed guidelines.
大多数多发性硬化症（MS）患者身体活动不足。身体活动指南是运动处方、促进和监测的重要工具。本文介绍了在为 MS 患者制定基于证据的身体活动指南时应用国际指南制定标准。该开发过程得到了评估指南研究和评估 II 工具的指导。指南的证据基础包括对研究的系统回顾，这些研究考察了运动对 MS 患者的身体健康、疲劳、移动能力和与健康相关的生活质量的影响。一个多学科共识小组审议了证据，并制定了指南和前言。对材料的专家和利益相关者审查导致了指南两个组成部分的措辞的细化。由此产生的指南指出，为了获得重要的健康益处，轻度至中度残疾的 MS 成年人每周至少需要进行 30 分钟的中等强度有氧运动 2 次，以及主要肌肉群的力量训练运动 2 次。满足这些指南要求还可能减轻疲劳、提高移动能力并改善与健康相关的生活质量的某些方面。鼓励 MS 患者和卫生专业人员采用这些经过严格制定的指南。
