State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, PR China.
Environ Toxicol Pharmacol. 2013 Sep;36(2):451-462. doi: 10.1016/j.etap.2013.05.007. Epub 2013 May 24.
With the development and application of carbon nanotubes (CNTs), the potential hazards of CNTs to biological systems and the environment are getting more and more attention. This review evaluated the effects of physicochemical properties of CNTs on toxicity and summarized the advances on the mechanism of CNTs toxicity. We also proposed the possible hazards associated with CNTs and harmful effects resulting from exposure of aquatic animals, bacteria and higher plants to CNTs in vitro and in vivo. The current knowledge and gaps on CNTs were outlined as a potential problem for the environment and human health. The current research gaps on CNTs toxicity were identified and the further studying focus was proposed, too. This essay concluded with a set of recommendations for the advancement of understanding of the role of CNTs and future challenges in environmental and ecotoxicological research.
随着碳纳米管(CNTs)的发展和应用,CNTs 对生物系统和环境的潜在危害越来越受到关注。本综述评估了 CNTs 的物理化学性质对毒性的影响,并总结了 CNTs 毒性机制的研究进展。我们还提出了与 CNTs 相关的可能危害以及水生动物、细菌和高等植物在体外和体内暴露于 CNTs 时产生的有害影响。概述了 CNTs 对环境和人类健康可能造成的问题方面的现有知识和差距。确定了 CNTs 毒性研究的空白,并提出了进一步的研究重点。本文最后提出了一系列建议,以推动对 CNTs 作用的理解,并为未来在环境和生态毒理学研究中的挑战提供参考。