Terakado Kunihiko, Yogo Takuya, Nezu Yoshinori, Harada Yasuji, Hara Yasushi, Tagawa Masahiro
Department of Veterinary Surgery, Nippon Veterinary and Life Science University, 1-7-1 Kyonancho, Musashino, Tokyo 180-8602, Japan.
J Vet Med Sci. 2013 Nov;75(11):1491-5. doi: 10.1292/jvms.12-0363. Epub 2013 Jun 18.
The aim of this study was to determine the efficacy of a colorimetric pupil light reflex (PLR) device (Melan-100(®), U.S.A.) in dogs with sudden acquired retinal degeneration syndrome (SARDS; 16 cases), progressive retinal atrophy (PRA; 10 cases) and optic pathway disease (6 cases). The colorimetric device detected PLR abnormality in 32, 16 and 9 eyes with SARDS, PRA and optic pathway disease, respectively, whereas white light detected PLR abnormality in 18, 11 and 9 eyes with SARDS, PRA and optic pathway disease, respectively. SARDS dogs displayed miosis, while optic pathway disease dogs displayed mydriasis in a blue light examination. Thus, colorimetric PLR may be a useful method for determining whether electroretinography (ERG) or magnetic resonance imaging (MRI) should be performed for dogs with acute blindness.
本研究的目的是确定一种比色瞳孔光反射(PLR)设备(美国的Melan-100®)对患有突然获得性视网膜变性综合征(SARDS,16例)、进行性视网膜萎缩(PRA,10例)和视神经通路疾病(6例)的犬的疗效。该比色设备分别在32只、16只和9只患有SARDS、PRA和视神经通路疾病的眼睛中检测到PLR异常,而白光分别在18只、11只和9只患有SARDS、PRA和视神经通路疾病的眼睛中检测到PLR异常。在蓝光检查中,SARDS犬表现为瞳孔缩小,而视神经通路疾病犬表现为瞳孔散大。因此,比色PLR可能是一种有用的方法,可用于确定对于急性失明的犬是否应进行视网膜电图(ERG)或磁共振成像(MRI)检查。