Virtanen T, Kalliokoski P, Vilhunen P, Taivainen A, Mäntyjärvi R
Department of Clinical Microbiology, University of Kuopio, Finland.
Allergy. 1990 Jul;45(5):354-62. doi: 10.1111/j.1398-9995.1990.tb00511.x.
The concentrations of swine epithelial antigen (SEA), swine urinary antigen (SUA) and swine feed antigen (SFA) were measured in swineries. SEA seems to be the most prevalent of the constituents measured. In the serum samples of the subjects studied, specific IgG antibodies against the antigens were frequently encountered. However, a difference was seen in the distribution of anti-SUA-IgG antibodies between swinery workers and a control group of students. The influence of the level of specific dust concentrations on specific antibody titers was studied statistically. Positive correlations were observed between stationary site SUA concentrations and anti-SUA-IgG and anti-SEA-IgG titers, respectively, pointing to an association between exposure and humoral response in swinery work. Consequently, our results suggest that the measurement of antibodies against SUA or its components could offer a basis for the estimation of the level of swinery work-related respiratory exposure and for monitoring the quality of the working environment in swineries.
在养猪场中测量了猪上皮抗原（SEA）、猪尿液抗原（SUA）和猪饲料抗原（SFA）的浓度。SEA似乎是所测成分中最普遍的。在所研究对象的血清样本中，经常遇到针对这些抗原的特异性IgG抗体。然而，在养猪场工人和学生对照组之间，抗SUA-IgG抗体的分布存在差异。对特定粉尘浓度水平对特异性抗体滴度的影响进行了统计学研究。分别观察到固定场所SUA浓度与抗SUA-IgG和抗SEA-IgG滴度之间存在正相关，这表明在养猪场工作中暴露与体液反应之间存在关联。因此，我们的结果表明，检测抗SUA或其成分的抗体可为评估养猪场工作相关的呼吸道暴露水平以及监测养猪场工作环境质量提供依据。
