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前列腺原发性淋巴瘤:两例病例报告及文献综述

Primary lymphomas of the prostate: two case reports and a review of the literature.

作者信息

Wang Chaojun, Jiang Peng, Li Jun

机构信息

Department of Urology, First Affiliated Hospital, College of Medicine, Zhejiang University, HangZhou City, ZheJiang Province, PR China.

出版信息

Contemp Oncol (Pozn). 2012;16(5):456-9. doi: 10.5114/wo.2012.31781. Epub 2012 Nov 20.

DOI:10.5114/wo.2012.31781
PMID:23788930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3687442/
Abstract

INTRODUCTION

Non-Hodgkin lymphoma (NHL) is a common disease, but primary lymphoma of the prostate is rare.

MATERIAL AND METHODS

Here we present two cases of primary NHL of the prostate and a review of the relevant literature.

RESULTS

Both of them had no abnormal lymph node or hepatolienal enlargement. The first case underwent prostatic biopsy which indicated that it was NHL. The patient underwent combination chemotherapy three times, then a radical cystoprostatectomy. In the second case, the prostatic biopsy was not helpful for diagnosis. Therefore a radical prostatectomy was performed before the proper chemotherapy been given. He died half a year later because of a cerebrovascular accident.

CONCLUSIONS

We think it is difficult to get an accurate early diagnosis when the lymphoma occurs only in the prostate. Even the prostatic biopsy could not provide clear evidence. Early and appropriate treatment can extend the survival time and improve the quality of life.

摘要

引言

非霍奇金淋巴瘤(NHL)是一种常见疾病,但原发性前列腺淋巴瘤却很罕见。

材料与方法

在此,我们呈现两例原发性前列腺NHL病例,并对相关文献进行综述。

结果

两例患者均无异常淋巴结或肝脾肿大。第一例患者接受前列腺活检,结果显示为NHL。该患者接受了三次联合化疗,随后进行了根治性膀胱前列腺切除术。第二例患者,前列腺活检对诊断无帮助。因此,在给予适当化疗之前进行了根治性前列腺切除术。半年后,他因脑血管意外死亡。

结论

我们认为,当淋巴瘤仅发生在前列腺时,很难获得准确的早期诊断。即使前列腺活检也无法提供明确证据。早期且适当的治疗可延长生存时间并提高生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbd/3687442/7cf7e10a5dfc/WO-16-19740-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbd/3687442/34b16f1a3aa0/WO-16-19740-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbd/3687442/c5a09201d8a8/WO-16-19740-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbd/3687442/b297c0c7e5b3/WO-16-19740-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbd/3687442/7cf7e10a5dfc/WO-16-19740-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbd/3687442/34b16f1a3aa0/WO-16-19740-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbd/3687442/c5a09201d8a8/WO-16-19740-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbd/3687442/b297c0c7e5b3/WO-16-19740-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cbd/3687442/7cf7e10a5dfc/WO-16-19740-g004.jpg

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High levels of serum prostate-specific antigen due to PSA producing follicular non-Hodgkin's lymphoma.
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Primary diffuse large B-cell lymphoma of the prostate in a young patient.一名年轻患者的原发性前列腺弥漫性大B细胞淋巴瘤
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Expression of the chemokine receptor CCR7 in prostate cancer presenting with generalized lymphadenopathy: report of a case, review of the literature, and analysis of chemokine receptor expression.趋化因子受体CCR7在伴有全身淋巴结病的前列腺癌中的表达:病例报告、文献综述及趋化因子受体表达分析
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