Shen Xiao-Yong, Lin Zhi-Feng, Lin Qiang, Ruan Zhen, Huang Hai-Long, Ju Chao-Qiang, Wang Jin
Department of Thoracic Surgery, Huadong Hospital, Shanghai Fudan University, Shanghai, China ; The authors wish it to be known that in their opinion, the first two authors should be regarded as joint first authors.
Contemp Oncol (Pozn). 2013;17(2):210-3. doi: 10.5114/wo.2013.34375. Epub 2013 Apr 29.
Sarcomatoid carcinoma (SC) is a rare primary malignant tumor in which both carcinomatous and sarcomatous elements occur. It can occur in many different organs and anatomical locations, such as the skin, thyroid gland, bone, urinary tract, breast, pancreas, liver and other areas. Of them, pulmonary sarcomatoid carcinoma (PSC) is a rare malignant cancer composed of sarcoma and sarcoma-like tumors with spindle or giant cell features. Here a case of a 75-year-old Chinese man with a six-month history of cough and hemoptysis is reported. Chest X-ray showed a tumor shadow in the left lung field. Chest computed tomography (CT) scan showed a lobulated mass in his left hilum and even the left pulmonary artery. Pleomorphic interstitial cells were found by bronchoscopic brushing. To establish a definitive diagnosis for PSC, a left pneumonectomy was performed. The pathological stage was IIB (pT2N1M0) based on the tumor node metastasis (TNM) staging system. The tumor's pathology, histology, immunohistochemistry and treatment methods are discussed.
肉瘤样癌（SC）是一种罕见的原发性恶性肿瘤，其中同时存在癌性和肉瘤性成分。它可发生于许多不同器官和解剖部位，如皮肤、甲状腺、骨骼、泌尿系统、乳腺、胰腺、肝脏及其他部位。其中，肺肉瘤样癌（PSC）是一种罕见的恶性肿瘤，由具有梭形或巨细胞特征的肉瘤和肉瘤样肿瘤组成。本文报道了一例75岁中国男性患者，有6个月咳嗽和咯血病史。胸部X线显示左肺野有肿瘤阴影。胸部计算机断层扫描（CT）显示左肺门甚至左肺动脉有分叶状肿块。经支气管镜刷检发现多形性间质细胞。为明确诊断PSC，行左肺切除术。根据肿瘤淋巴结转移（TNM）分期系统，病理分期为IIB期（pT2N1M0）。对肿瘤的病理、组织学、免疫组化及治疗方法进行了讨论。
