Division of Hypothalamic Research, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.
Trends Neurosci. 2013 Sep;36(9):504-12. doi: 10.1016/j.tins.2013.05.003. Epub 2013 Jun 19.
Neurons within the central nervous system receive humoral and central (neurotransmitter or neuropeptide) signals that ultimately regulate ingestive behavior and metabolism. Recent advances in mouse genetics combined with neuroanatomical and electrophysiological techniques have contributed to a better understanding of these central mechanisms. This review integrates recently defined cellular mechanisms and neural circuits relevant to the regulation of feeding behavior, energy expenditure, and glucose homeostasis by metabolic signals.
中枢神经系统内的神经元接收体液和中枢（神经递质或神经肽）信号，这些信号最终调节摄食行为和代谢。近年来，小鼠遗传学的进展结合神经解剖学和电生理学技术，有助于更好地理解这些中枢机制。本综述整合了最近定义的与代谢信号调节摄食行为、能量消耗和葡萄糖稳态相关的细胞机制和神经回路。
