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伴有先天性毛细血管扩张性大理石样皮肤样损害的新生儿皮肤型红斑狼疮。

Cutaneous neonatal lupus with cutis marmorata telangiectatica congenita-like lesions.

作者信息

Trevisan Flávia, Cunha Paulo Rowilson, Pinto Clóvis Antonio Lopes, Cattete Fernanda Gomes

机构信息

Medical School of Jundiaí, Jundiai, SP, Brazil.

出版信息

An Bras Dermatol. 2013 May-Jun;88(3):428-31. doi: 10.1590/abd1806-4841.20131832.

Abstract

Neonatal lupus is a rare disease caused by the transplacental transfer of maternal autoantibodies to the foetus, characterized by transient clinical manifestations such as cutaneous, haematological, and hepatobiliary events or permanent such as congenital heart block. The typical cutaneous manifestations include erythematous, scaly, annular or arched lesions on the face, with slight central atrophy and photosensitivy, clinically and histologically similar to subacute cutaneous lupus. However, in some cases, the lesions may resemble those in cutis marmorata telangiectatica congenita, although this phenomenon is rare and only eight such cases have been reported to date. We report a case of cutaneous neonatal lupus with atypical lesions on the limbs, which had a reddish-purple marbled appearance, resembling the lesions in cutis marmorata telangiectatica congenita.

摘要

新生儿红斑狼疮是一种罕见疾病,由母体自身抗体经胎盘转移至胎儿所致,其特征为有短暂临床表现,如皮肤、血液学及肝胆系统病变,或有永久性病变,如先天性心脏传导阻滞。典型的皮肤表现为面部出现红斑、鳞屑、环状或弓形损害,中央有轻度萎缩并伴有光敏性,临床及组织学表现与亚急性皮肤型红斑狼疮相似。然而,在某些病例中,损害可能类似先天性毛细血管扩张性大理石样皮肤,不过这种现象罕见,迄今为止仅报道过8例。我们报告1例四肢有非典型损害的皮肤型新生儿红斑狼疮病例,其损害呈红紫色大理石样外观,类似先天性毛细血管扩张性大理石样皮肤的损害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7485/3754378/49bf1caa3e7e/abd-88-0428-g01.jpg

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