Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Bezmialem Vakif University, Istanbul, Turkey.
Wien Klin Wochenschr. 2013 Jul;125(13-14):368-70. doi: 10.1007/s00508-013-0378-3. Epub 2013 Jun 21.
The aim of this study was to search rubella prevalence and compare the results with national and international data.
The presence of anti-rubella immunoglobulin G (IgG) and anti-rubella immunoglobulin M (IgM) antibodies were studied in the sera obtained from cases with fever in last week and applied to the Microbiology Laboratory in the period between February 2010 and December 2010. No clinical sign or symptom regarding rubella infection has been evaluated for cases to obtain blood samples. IgM and IgG antibodies were tested with ELISA (Vitros ECI Q (J&J) Company Ortho Clinical Diagnostic Macro) method. The data obtained were assessed with SPSS statistical package using chi-square trend analysis method.
Anti-rubella IgM positivity was found 8/68 (8.8 %) of males and 3/138 (2.2 %) of females who are under 18 years-old (p = 0.028). Meanwhile 47/65 (72.3 %) of males and 99/122 (81.8 %) of females under 18 years-old were presented with anti-rubella IgG positivity (p = 0.164). In all, 2/8 (25 %) males and 28/1,181 (2.4 %) females older than 18 years-old were anti-rubella IgM positive (p = 0.013). Anti-rubella IgG antibodies were found positive in 862/1,181 (73 %) of females and all males (8/8) older than 18-years-old (p = 0.086).
In spite of the active immunization programme commenced after 2006, rubella infection is still a risk in Turkey without discriminating the gender.
本研究旨在调查风疹的流行情况，并与国内外数据进行比较。
在 2010 年 2 月至 12 月期间，从最近一周发热的患者血清中检测抗风疹免疫球蛋白 G（IgG）和抗风疹免疫球蛋白 M（IgM）抗体，将这些血清应用于微生物学实验室。在采集这些患者的血样时，并未评估他们是否有与风疹感染相关的临床症状或体征。IgM 和 IgG 抗体采用 ELISA（强生 Vitros ECI Q（J&J）公司 Ortho 临床诊断 Macro）法进行检测。采用 SPSS 统计软件包对获得的数据进行评估，采用卡方趋势分析方法。
18 岁以下的男性中，抗风疹 IgM 阳性率为 8/68（8.8%），女性为 3/138（2.2%），差异有统计学意义（p=0.028）。同时，18 岁以下的男性中，抗风疹 IgG 阳性率为 47/65（72.3%），女性为 99/122（81.8%），差异无统计学意义（p=0.164）。在 18 岁以上的人群中，男性中抗风疹 IgM 阳性的有 2/8（25%），女性有 28/1181（2.4%），差异有统计学意义（p=0.013）。18 岁以上的女性中，抗风疹 IgG 抗体阳性的有 862/1181（73%），所有男性均为阳性（8/8），差异无统计学意义（p=0.086）。
尽管 2006 年后开始了主动免疫接种计划，但在土耳其，风疹感染仍然是一个风险，且不分性别。
