Infectious Diseases Unit, Hospital General Universitario de Elche, Alicante, Spain.
J Med Virol. 2012 Mar;84(3):548-50. doi: 10.1002/jmv.23195.
A cross-sectional study of seroprevalence of rubella antibodies was carried out in all immigrant pregnant women (1,627) from February 2006 to June 2010. For each immigrant woman one Spanish pregnant woman was recruited. The seroprevalence of IgG antibodies against rubella in immigrant women was 92% (95% confidence interval [CI]: 90.4-93.3), and in native women was 97.7% (95%CI: 96.7-98.4) (P < 0.001). Immunity against was lowest among women from Latin America (odds ratio [OR]: 0.17), followed by women from Asia (OR: 0.20), Sub-Saharan Africa (OR: 0.27) and Northern Africa (OR: 0.37). Female immigrants from developing countries should be targeted for immunization to reduce the risk of congenital rubella.
本研究于 2006 年 2 月至 2010 年 6 月对所有移民孕妇（1627 名）进行了横断面研究，以调查其风疹抗体的血清流行率。为每位移民孕妇招募了一名西班牙孕妇作为对照。移民孕妇的风疹 IgG 抗体血清流行率为 92%（95%置信区间[CI]：90.4-93.3），而本地孕妇的流行率为 97.7%（95%CI：96.7-98.4）（P<0.001）。来自拉丁美洲的女性（比值比[OR]：0.17）、亚洲（OR：0.20）、撒哈拉以南非洲（OR：0.27）和北非（OR：0.37）的女性对风疹的免疫力最低。应针对来自发展中国家的女性移民进行免疫接种，以降低先天性风疹的风险。
