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胃食管结合部腺癌患者行全胃切除术后的短期结局:腹腔镜与开腹胃切除术——一项回顾性队列研究。

The short-term outcome in esophagogastric junctional adenocarcinoma patients receiving total gastrectomy: laparoscopic versus open gastrectomy--a retrospective cohort study.

机构信息

State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032 Shaanxi Province, China.

出版信息

Int J Surg. 2013;11(9):957-61. doi: 10.1016/j.ijsu.2013.06.010. Epub 2013 Jun 21.

DOI:10.1016/j.ijsu.2013.06.010
PMID:23796445
Abstract

OBJECTIVE

This study aimed to compare the quality of life in Siewert type II esophagogastric junctional adenocarcinoma patients receiving either laparoscopic total gastrectomy or open total gastrectomy.

METHODS

From Sep 1, 2008 to May 1, 2012, totally 204 consecutive patients with Siewert type II esophagogastric junctional adenocarcinoma were involved in this retrospective study. Patients were assigned to receive either laparoscopic total gastrectomy or open total gastrectomy. Details concerning the postoperative outcomes and the quality of life questionnaire were collected and compared.

RESULTS

Totally 104 patients were involved in the open gastrectomy group and 100 in the laparoscopic gastrectomy group. No differences were noted between the groups in demographics, blood loss, anastomotic leak, anastomotic stricture, hospital stay, reoperation and in-hospital mortality. Totally 188 cases of patients (92.16%) responded to the questionnaire measures during the entire follow-up period, including 93 (93%) in the laparoscopic group and 95 (91.35%) in the open group. The score of every scale and item in laparoscopic group improved much more quickly comparing with the open group, suggesting that patients in laparoscopic group recovered much more quickly than those in open group.

CONCLUSIONS

Laparoscopic total gastrectomy could lead to a significant improvement of the short-term benefits for patients with esophagogastric junctional adenocarcinoma as compared with open group.

摘要

目的

本研究旨在比较接受腹腔镜全胃切除术与开放性全胃切除术的 Siewert Ⅱ型食管胃结合部腺癌患者的生活质量。

方法

本回顾性研究纳入了 2008 年 9 月 1 日至 2012 年 5 月 1 日期间 204 例连续的 Siewert Ⅱ型食管胃结合部腺癌患者。患者被分配接受腹腔镜全胃切除术或开放性全胃切除术。收集并比较了术后结果和生活质量问卷调查的详细信息。

结果

开放性胃切除术组 104 例,腹腔镜胃切除术组 100 例。两组患者在人口统计学、出血量、吻合口漏、吻合口狭窄、住院时间、再次手术和住院死亡率方面无差异。在整个随访期间,共有 188 例患者(92.16%)对问卷措施做出了回应,其中腹腔镜组 93 例(93%),开放性组 95 例(91.35%)。腹腔镜组的每个量表和项目的评分恢复得更快,表明腹腔镜组患者的恢复速度明显快于开放性组。

结论

与开放性手术相比,腹腔镜全胃切除术可显著改善食管胃结合部腺癌患者的短期获益。

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