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英国育肥猪单位中沙门氏菌感染的半随机模型。

Semi-stochastic models for Salmonella infection within finishing pig units in the UK.

机构信息

Institute of Infection & Global Health, Department of Epidemiology & Population Health, University of Liverpool, Leahurst Campus, Chester High Road, Neston, Cheshire CH64 7TE, UK.

出版信息

Math Biosci. 2013 Oct;245(2):148-56. doi: 10.1016/j.mbs.2013.06.004. Epub 2013 Jun 21.

Abstract

A multi-group semi-stochastic model is formulated to describe Salmonella dynamics on a pig herd within the UK and assess whether farm structure has any effect on the dynamics. The models include both direct transmission and indirect (via free-living infectious units in the environment and airborne infection). The basic reproduction number R0 is also investigated. The models estimate approximately 24.6% and 25.4% of pigs at slaughter weight will be infected with Salmonella within a slatted-floored and solid-floored unit respectively, which corresponds to values found in previous abattoir and farm studies, suggesting that the model has reasonable validity. Analysis of the models identified the shedding rate to be of particular importance in the control of Salmonella spread, a finding also evident in an increase in the R0 value.

摘要

建立了一个多群组半随机模型来描述英国猪群中的沙门氏菌动态,并评估农场结构对动态是否有影响。该模型包括直接传播和间接传播(通过环境中的自由生活感染单元和空气传播感染)。还研究了基本繁殖数 R0。模型估计,在有漏缝地板和实心地板的猪舍中,分别有大约 24.6%和 25.4%的待宰肥猪感染沙门氏菌,这与之前屠宰场和农场研究中的发现相符,表明该模型具有合理的有效性。模型分析确定,在控制沙门氏菌传播方面,粪便排出率非常重要,这一发现也体现在 R0 值的增加上。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb49/3791402/38bd1cc57980/gr1.jpg

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