Paliwal Nidhi, Gupta Kumud, Dewan R K, Mullick Shalini
Department of Pathology, LRS Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
Indian J Chest Dis Allied Sci. 2013 Jan-Mar;55(1):39-41.
Mature teratoma is a common anterior mediastinal tumour. However, occurrence of transformed malignant component within it is very rare. We report a case of a 32-year-old female presenting with dry cough and chest pain. Contrast-enhanced computed tomography (CT) showed a large thin-walled cystic lesion measuring 11.4 cm x 10.6 cm x 10.0 cm in the anterior mediastinum. Right postero-lateral thoracotomy was performed and the tumour was completely excised. Histopathological examination of the excised specimen was suggestive of mature teratoma with transformed malignant component, adenocarcinoma (somatic-type malignancy).
成熟畸胎瘤是一种常见的前纵隔肿瘤。然而，其内部出现转化的恶性成分非常罕见。我们报告一例32岁女性，表现为干咳和胸痛。增强计算机断层扫描（CT）显示前纵隔有一个大的薄壁囊性病变，大小为11.4 cm×10.6 cm×10.0 cm。行右后外侧开胸手术，肿瘤被完整切除。切除标本的组织病理学检查提示为成熟畸胎瘤伴转化的恶性成分，即腺癌（体细胞型恶性肿瘤）。
