Gupta Pallav, Singh Shubhra, Yadava Kamlesh, Kumari Niraj
Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Asian Cardiovasc Thorac Ann. 2012 Feb;20(1):80-2. doi: 10.1177/0218492311428185.
Teratoma is the second most common mediastinal neoplasm, but malignant transformation in mature teratomas is uncommon at both gonadal and extragonadal sites. A 35-year-old woman presented with an anterior mediastinal mass. Computed tomography suggested a teratoma. Meticulous pathological examination helped in detecting a neuroendocrine neoplasm (carcinoid) within the mature teratoma. Malignant transformation in a teratoma is difficult to diagnose on clinical and radiological assessment; histopathology is essential to detect the malignant nature of these neoplasms.
畸胎瘤是第二常见的纵隔肿瘤，但成熟畸胎瘤发生恶性转化在性腺和性腺外部位均不常见。一名35岁女性因前纵隔肿块就诊。计算机断层扫描提示为畸胎瘤。细致的病理检查有助于在成熟畸胎瘤内检测到神经内分泌肿瘤（类癌）。畸胎瘤的恶性转化在临床和影像学评估中难以诊断；组织病理学对于检测这些肿瘤的恶性性质至关重要。
