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肾移植患者围产期麻醉管理——一项多中心队列研究

Peripartum anesthetic management of renal transplant patients--a multicenter cohort study.

作者信息

Ioscovich A, Orbach-Zinger S, Zemzov D, Reuveni A, Eidelman L A, Ginosar Y

机构信息

Department of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center, Hebrew University Jerusalem , Israel .

出版信息

J Matern Fetal Neonatal Med. 2014 Mar;27(5):484-7. doi: 10.3109/14767058.2013.818973. Epub 2013 Jul 26.

Abstract

As the number and success of renal transplantation has grown, there has been an increase in the number of renal transplant patients giving birth. To date, there has been no data on obstetric anesthesia management of these patients. The purpose of this study was to build an Israeli national database on parturients after renal transplant. A sixteen-year (calendar years 1996-2011) retrospective study was conducted at three major tertiary centers with a combined current birth rate of approximately 25,000 deliveries annually. We found 83 labors in 64 women. Forty-two percent of this population suffered from hypertension while 12.5% had diabetes. Forty-seven percent of women had a vaginal delivery while 53% of women had a cesarean section. The rate of epidural analgesia for labor was 59%, and rate of regional anesthesia during cesarean section was 75%. There were no anesthetic complications in any cases. Standard ASA monitoring was used in all cases except for one woman with severe hypertension who required an arterial line during her cesarean section. Forty-seven percent of newborn were under 37 weeks with average gestational week 36 ± 3 days and birth weight 2.5 ± 0.7 kg. Average Apgar was 8.4 ± 1.3 at one minute and 9.3 ± 0.7 at five minutes. There was one neonatal death in the CS group due to placental abruption. Patients after renal transplant can safely undergo birth and obstetric analgesia.

摘要

随着肾移植数量的增加及其成功率的提高,肾移植后分娩的患者数量也在上升。迄今为止,尚无关于这些患者产科麻醉管理的数据。本研究的目的是建立一个以色列肾移植后产妇的国家数据库。在三个主要的三级中心进行了一项为期16年(1996 - 2011历年)的回顾性研究,这三个中心目前的年分娩率合计约为25000例。我们在64名女性中发现了83次分娩。该人群中42%患有高血压,12.5%患有糖尿病。47%的女性经阴道分娩,53%的女性行剖宫产。分娩时硬膜外镇痛率为59%,剖宫产时区域麻醉率为75%。所有病例均无麻醉并发症。除一名患有严重高血压的女性在剖宫产期间需要动脉置管外,所有病例均采用标准的美国麻醉医师协会(ASA)监测。47%的新生儿孕周不足37周,平均孕周为36±3天,出生体重为2.5±0.7千克。1分钟时平均阿氏评分8.4±1.3,5分钟时为9.3±0.7。剖宫产组有1例新生儿因胎盘早剥死亡。肾移植后的患者可以安全地进行分娩和产科镇痛。

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