沙特健康非吸烟成年人的肺量计参考值。
Spirometric reference values for healthy nonsmoking Saudi adults.
作者信息
Al Ghobain Mohammed O, Alhamad Esam H, Alorainy Hassan S, Al Hazmi Manal, Al Moamary Mohamed S, Al-Hajjaj Mohamed S, Idress Majdy, Al-Jahdali Hamdan, Zeitouni Mohammed
机构信息
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
出版信息
Clin Respir J. 2014 Jan;8(1):72-8. doi: 10.1111/crj.12038. Epub 2013 Jul 31.
OBJECTIVES
To derive prediction equations of spirometric values of healthy Saudi adults and to compare the derived equations with equations reported in selected population.
METHODS
Cross-sectional study of healthy nonsmoking men and women Saudi adults. The measured spirometric values were the forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1 ), peak expiratory flow (PEF) and forced mid-expiratory flow (FEF 25%-75%).
RESULTS
A total of 621 spirometric tests were done. The prediction equations were derived using the following formula: Predicted spirometric value = constant + (b1 × age) + (b2 × height (cm)), where b1 and b2 represent the regression coefficients for age and height, respectively. Variable Constant Age (years) Height (cm) Variable Constant Age (years) Height (cm) Males (n = 292) Females (n = 175) FVC -2.933 -0.018 0.046 FVC -3.470 -0.016 0.045 FEV1 -1.886 -0.019 0.036 FEV1 -2.482 -0.018 0.036 FEV1 /FVC (%) 98.41 -0.095 -0.068 FEV1 /FVC (%) 100.67 -0.142 -0.072 PEF 17.274 -1.243 3.471 PEF -226.648 -0.499 4.076 FEF25%-75% 0.100 -0.024 0.027 FEF25%-75% -1.337 -0.021 0.031 The means of the measured FVC and FEV1 were significantly lower than the predicted values derived by the American equations of -7.2% and -4.6% among males, respectively (P value < 0.00001), and -4.7%, and -5.26% among females, respectively (P value < 0.00001).
CONCLUSION
The reference spirometric values derived in our study were significantly lower than the predicted values derived by the American equations.
目的
推导沙特健康成年人肺功能测定值的预测方程，并将推导的方程与选定人群中报告的方程进行比较。
方法
对沙特健康非吸烟成年男性和女性进行横断面研究。测量的肺功能测定值为用力肺活量（FVC）、1秒用力呼气量（FEV1）、呼气峰值流速（PEF）和用力呼气中期流速（FEF 25%-75%）。
结果
共进行了621次肺功能测试。预测方程使用以下公式推导：预测肺功能测定值 = 常数 + （b1×年龄） + （b2×身高（厘米）），其中b1和b2分别代表年龄和身高的回归系数。
|变量|常数|年龄（岁）|身高（厘米）|
|----|----|----|----|
|男性（n = 292）|FVC|-2.933|-0.018|0.046|
|男性（n = 292）|FEV1|-1.886|-0.019|0.036|
|男性（n = 292）|FEV1/FVC（%）|98.41|-0.095|-0.068|
|男性（n = 292）|PEF|17.274|-1.243|3.471|
|男性（n = 292）|FEF25%-75%|0.100|-0.024|0.027|
|女性（n = 175）|FVC|-3.470|-0.016|0.045|
|女性（n = 175）|FEV1|-2.482|-0.018|0.036|
|女性（n = 175）|FEV1/FVC（%）|100.67|-0.142|-0.072|
|女性（n = 175）|PEF|-226.648|-0.499|$4.076$|
|女性（n = 175）|FEF25%-75%|-1.337|-0.021|0.031|
男性中，实测FVC和FEV1的平均值分别比美国方程推导的预测值低7.2%和4.6%，差异有统计学意义（P值<0.00001）；女性中分别低4.7%和5.26%，差异有统计学意义（P值<0.00001）。
结论
我们研究中得出的肺功能参考值明显低于美国方程推导的预测值。
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