Department of Psychiatry, Medical University of Białystok, Choroszcz, Poland.
Alcohol Clin Exp Res. 2013 Aug;37(8):1261-3. doi: 10.1111/acer.12208. Epub 2013 Jun 25.
Most of the clinical, histopathological, and biochemical studies consider the effect of chronic alcohol intoxication on myocardial injury. Much less attention has been paid to acute alcohol (binge drinking)-induced cardiotoxicity, even though alcohol binging is much more common than alcohol dependence.
We briefly present some of the binge drinking-induced "holiday heart" effects. The literature was searched to find effects of alcohol on heart.
In binge drinking, the literature has demonstrated transient myocardial subtle changes in cardiac magnetic resonance, increased serological markers of myocardial injury and inflammation, abnormal cardiac rhythm, changes in other biochemical and ultrastructural indices of myocardial dysfunction, as well as changes in metabolism, blood pressure, heart rate, thrombosis/fibrinolysis processes, and coronary vasoconstriction.
Although acute low alcohol exposure has widely proven positive effect on myocardial function, heavy acute drinking frequent events are related to adverse cardiovascular effects.
大多数临床、组织病理学和生物化学研究都考虑了慢性酒精中毒对心肌损伤的影响。而急性酒精（狂饮）引起的心脏毒性则较少受到关注，尽管酒精狂饮比酒精依赖更为常见。
我们简要介绍了一些狂饮引起的“假日心脏”效应。我们检索了文献以查找酒精对心脏的影响。
在狂饮中，文献已经证明了心脏磁共振中短暂的心肌细微变化、心肌损伤和炎症的血清标志物增加、心律失常、其他心肌功能的生化和超微结构指标的变化，以及代谢、血压、心率、血栓形成/纤溶过程和冠状动脉收缩的变化。
尽管急性低酒精暴露已被广泛证明对心肌功能有积极影响，但频繁发生的重度急性饮酒与不良心血管效应有关。
