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感染艾滋病毒患者中丙型和乙型肝炎病毒的流行情况:缅甸一项大型艾滋病毒护理项目的横断面分析

Prevalence of hepatitis C and B virus among patients infected with HIV: a cross-sectional analysis of a large HIV care programme in Myanmar.

作者信息

Zaw Sai Ko Ko, Tun Sai Thein Than, Thida Aye, Aung Thet Ko, Maung Win, Shwe Myint, Aye Mar Mar, Clevenbergh Phillipe

机构信息

International Union Against Tuberculosis and Lung Disease, Mandalay, Myanmar.

出版信息

Trop Doct. 2013 Jul;43(3):113-5. doi: 10.1177/0049475513493416. Epub 2013 Jun 25.

DOI:10.1177/0049475513493416
PMID:23800421
Abstract

Co-infection with the hepatitis C virus (HCV) and/or hepatitis B virus (HBV) influences the morbidity and mortality of patients with HIV. A cross sectional analysis was of 11,032 HIV-infected patients enrolled in the Integrated HIV Care Program from May 2005 to April 2012 and Epi-info 3.5 was used to determine the serological prevalence of chronic hepatitis B and hepatitis C. The mean ± standard deviation age of patients was 36 ± 8.4 years (adult cohort) and 7 ± 3 years (paediatric cohort). The sero prevalence of hepatitis B surface antigen, hepatitis C (anti HCV antibodies) and triple infection are 8.7%, 5.3% and 0.35%, respectively. Men who have sex with men are at the highest risk of being co-infected with hepatitis B while intravenous drug users are at the highest risk of being co-infected with hepatitis C. It is important to screen for hepatitis B and C in HIV infected people in order to provide quality care for HIV patients with co-infection.

摘要

丙型肝炎病毒(HCV)和/或乙型肝炎病毒(HBV)合并感染会影响HIV患者的发病率和死亡率。对2005年5月至2012年4月纳入综合HIV护理项目的11032例HIV感染患者进行了横断面分析,并使用Epi-info 3.5确定慢性乙型肝炎和丙型肝炎的血清学患病率。患者的平均年龄±标准差为36±8.4岁(成人队列)和7±3岁(儿科队列)。乙型肝炎表面抗原、丙型肝炎(抗HCV抗体)和三重感染的血清流行率分别为8.7%、5.3%和0.35%。男男性行为者感染乙型肝炎的风险最高,而静脉吸毒者感染丙型肝炎的风险最高。对HIV感染者进行乙型和丙型肝炎筛查很重要,以便为合并感染的HIV患者提供优质护理。

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