蛋糕：用于癌症基因组中体细胞变异的综合分析的生物信息学管道。
Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes.
机构信息
Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.
出版信息
Bioinformatics. 2013 Sep 1;29(17):2208-10. doi: 10.1093/bioinformatics/btt371. Epub 2013 Jun 25.
Abstract
We have developed Cake, a bioinformatics software pipeline that integrates four publicly available somatic variant-calling algorithms to identify single nucleotide variants with higher sensitivity and accuracy than any one algorithm alone. Cake can be run on a high-performance computer cluster or used as a stand-alone application. Availabilty: Cake is open-source and is available from http://cakesomatic.sourceforge.net/
摘要
我们开发了 Cake，这是一个生物信息学软件管道，集成了四个公开的体细胞变异调用算法，可识别单核苷酸变异，其敏感性和准确性均高于任何单一算法。Cake 可以在高性能计算机集群上运行，也可以作为独立的应用程序使用。可用性：Cake 是开源的，可从 http://cakesomatic.sourceforge.net/ 获取。
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