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一名患有慢性肉芽肿病的儿童因一种新发现的假单胞菌引起的肺炎。

Pneumonia caused by a newly recognized pseudomonad in a child with chronic granulomatous disease.

作者信息

Trotter J A, Kuhls T L, Pickett D A, Reyes de la Rocha S, Welch D F

机构信息

Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City.

出版信息

J Clin Microbiol. 1990 Jun;28(6):1120-4. doi: 10.1128/jcm.28.6.1120-1124.1990.

DOI:10.1128/jcm.28.6.1120-1124.1990
PMID:2380349
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC267888/
Abstract

A pseudomonad was isolated from the pleural fluid and pulmonary decortication tissue of a 5-year-old child with chronic granulomatous disease. Although the isolate was phenotypically similar to Pseudomonas cepacia, its biochemical profile was more similar to that of Pseudomonas pickettii biovar 2. Its slow growth rate, ability to hydrolyze urea rapidly, and lateral and polar flagellar pattern were suggestive of Oligella ureolytica (formerly CDC group IVe). The cellular fatty acid composition was similar to that of P. cepacia and Pseudomonas gladioli, except for the presence of dodecanoic acid. Numerical analysis of the fatty acid data supported the interrelatedness of the isolate with other species of the pseudomallei group (rRNA homology group II) of Pseudomonas. The organism described in this report is an addition to the growing list of catalase-positive organisms which can potentially cause severe morbidity in patients with chronic granulomatous disease.

摘要

从一名患有慢性肉芽肿病的5岁儿童的胸腔积液和肺剥脱组织中分离出一株假单胞菌。尽管该分离株在表型上与洋葱伯克霍尔德菌相似,但其生化特征更类似于皮氏假单胞菌生物变种2。其生长速度缓慢、能快速水解尿素以及具有侧生和极生鞭毛模式提示为解脲寡养单胞菌(以前的CDC IVe组)。细胞脂肪酸组成与洋葱伯克霍尔德菌和唐菖蒲假单胞菌相似,只是存在十二烷酸。脂肪酸数据的数值分析支持该分离株与假单胞菌类鼻疽菌群(rRNA同源性组II)的其他物种具有相关性。本报告中描述的这种微生物是过氧化氢酶阳性微生物不断增加的名单中的又一例,这些微生物可能会在慢性肉芽肿病患者中导致严重发病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e215/267888/08797be28faf/jcm00054-0056-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e215/267888/08797be28faf/jcm00054-0056-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e215/267888/08797be28faf/jcm00054-0056-a.jpg

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Cellular fatty acid composition of Pseudomonas marginata and closely associated bacteria.边缘假单胞菌及密切相关细菌的细胞脂肪酸组成
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Pseudomonas cepacia: an emerging pathogen in chronic granulomatous disease.洋葱伯克霍尔德菌:慢性肉芽肿病中的一种新兴病原体。
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