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用于评估脆弱拟杆菌肠道毒力的兔模型。

Rabbit model to evaluate enterovirulence of Bacteroides fragilis.

作者信息

Myers L L, Shoop D S, Collins J E

机构信息

Veterinary Research Laboratory, Montana State University, Bozeman 59717.

出版信息

J Clin Microbiol. 1990 Jul;28(7):1658-60. doi: 10.1128/jcm.28.7.1658-1660.1990.

Abstract

Enterotoxigenic Bacteroides fragilis elicited fluid accumulation in the intestinal tract and exfoliation of epithelial cells in the proximal colon of the 2-week-old rabbit. The rabbit model was employed to screen isolates of B. fragilis for enterovirulence and to study the pathogenesis of disease caused by enterotoxigenic B. fragilis.

摘要

产肠毒素脆弱拟杆菌可引起2周龄家兔肠道积液和近端结肠上皮细胞脱落。该家兔模型用于筛选脆弱拟杆菌分离株的肠毒性,并研究产肠毒素脆弱拟杆菌所致疾病的发病机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef0e/268010/19962e6d1335/jcm00055-0179-a.jpg

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