Shah N, Osea E A, Martinez G J
Long Beach Veterans Administration Healthcare System, Long Beach, CA, USA.
Innovative Clinical Research, Inc., Harbor City, CA, USA.
Int J Lab Hematol. 2014 Feb;36(1):56-61. doi: 10.1111/ijlh.12118. Epub 2013 Jun 27.
Hemoglobin concentration is assessed to detect anemia and its associated morbidities. Hemoglobin is usually determined from venous or capillary blood samples run on a laboratory analyzer. However, this method requires a needle stick and results can be delayed. It also exposes caregivers to risks associated with needle sticks and blood exposure. Noninvasive hemoglobin determination would be of benefit to patients and caregivers because it would allow for quick and painless point-of-care assessment.
Hemoglobin determination from a noninvasive spot check hemoglobin device (Pronto-7 with SpHb, Masimo) and an invasive point-of-care device (HemoCue) was compared with venous blood samples run on a laboratory hematology analyzer.
A total of 440 outpatients and healthy volunteers were included (mean age 36 years, 62% female). Compared with the hematology analyzer, the bias ± standard deviation of was -0.1 ± 1.1 g/dL for SpHb and -0.1 ± 1.6 g/dL for HemoCue.
Noninvasive hemoglobin testing with SpHb provided similar accuracy as invasive point-of-care hemoglobin testing and may enable more efficient and effective patient care.
评估血红蛋白浓度以检测贫血及其相关疾病。血红蛋白通常通过在实验室分析仪上检测静脉血或毛细血管血样来测定。然而，这种方法需要针刺采血，结果可能会延迟。它还使护理人员面临与针刺和血液暴露相关的风险。无创血红蛋白测定对患者和护理人员有益，因为它可以实现快速且无痛的即时护理评估。
将一种无创即时血红蛋白检测设备（带有SpHb的Pronto-7，Masimo公司）和一种有创即时护理设备（HemoCue）测定的血红蛋白结果与在实验室血液分析仪上检测的静脉血样结果进行比较。
共纳入440名门诊患者和健康志愿者（平均年龄36岁，62%为女性）。与血液分析仪相比，SpHb的偏差±标准差为-0.1±1.1 g/dL，HemoCue的偏差±标准差为-0.1±1.6 g/dL。
使用SpHb进行无创血红蛋白检测与有创即时护理血红蛋白检测具有相似的准确性，可能会使患者护理更高效、更有效。
