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一期和两期肱动脉-贵要静脉动静脉内瘘术的结果比较。

A comparison of the outcomes of one-stage and two-stage brachiobasilic arteriovenous fistulas.

机构信息

Renal Department, King's College Hospital, London, United Kingdom; Department of Nephrology and Transplantation, Guy's Hospital, London, United Kingdom.

出版信息

J Vasc Surg. 2013 Nov;58(5):1300-4. doi: 10.1016/j.jvs.2013.05.030. Epub 2013 Jun 28.

Abstract

OBJECTIVE

The brachiobasilic arteriovenous fistula (BBAVF) can be formed in one or two stages. This study examined the failure rates and functional patencies of one-stage vs two-stage brachiobasilic transposition fistulas to compare the two surgical techniques.

METHODS

We retrospectively identified all the patients who underwent BBAVF access surgery at King's College Hospital between January 1, 2009, and December 31, 2011 (3 years). Patients were divided into two groups according to one-stage or two-stage procedure. All patients were seen in the access clinic 4 to 6 weeks postoperatively, and their fistulas were scanned (duplex). The surveillance of fistulas consists of duplex scans every 6 months to assess volume flow.

RESULTS

During the study interval, 149 brachiobasilic transpositions (65 one-stage and 84 two-stage) were performed in 141 patients. Patients undergoing the two-stage procedure had a smaller mean preoperative vein diameter (4.0 ± 1.1 vs 3.6 ± 1.3 mm; P = .041) and tended to be older (58 ± 15 vs 63 ± 15 years; P = .062). Mean overall follow-up was 559 ± 333 days. There was no difference in primary failure between the two groups (45% vs 42%; P = .718). At 1 year, the two-stage BBAVFs had significantly better primary (71% vs 87%; P = .034), assisted primary (77% vs 95%; P = .017), and secondary functional (79% vs 95%; P = .026) patencies. The same applied to 2-year primary (53% vs 75%; P = .034), assisted primary (57% vs 77%; P = .017), and secondary functional (57% vs 77%; P = .026) patencies. Multivariate Cox regression showed that the one-stage procedure was 3.2 times more likely to fail (P = .028). Men were 2.7 times more likely to lose their access (P = .054).

CONCLUSIONS

This study describes a large series of BBAVFs and makes an extensive comparison between the one-stage and two-stage operations. Significantly improved overall functional patency is demonstrated for the two-stage operation.

摘要

目的

肱动脉-正中静脉动静脉内瘘(BBAVF)可分一期或两期形成。本研究比较了一期与两期肱动脉正中静脉转位内瘘的失败率和功能通畅率,以评估两种手术技术。

方法

我们回顾性地确定了 2009 年 1 月 1 日至 2011 年 12 月 31 日(3 年)期间在国王学院医院接受 BBAVF 通路手术的所有患者。根据一期或两期手术将患者分为两组。所有患者术后 4-6 周在通路门诊就诊,对其瘘管进行扫描(双功能超声)。瘘管的监测包括每 6 个月进行一次双功能超声扫描,以评估容量流量。

结果

在研究期间,141 例患者进行了 149 例肱动脉正中静脉转位(65 例一期,84 例两期)。行两期手术的患者术前静脉平均直径较小(4.0±1.1 毫米比 3.6±1.3 毫米;P=0.041),且年龄较大(58±15 岁比 63±15 岁;P=0.062)。平均总随访时间为 559±333 天。两组的主要失败率无差异(45%比 42%;P=0.718)。1 年时,两期 BBAVF 的主要(71%比 87%;P=0.034)、辅助性主要(77%比 95%;P=0.017)和继发性功能(79%比 95%;P=0.026)通畅率明显更好。2 年时同样如此,主要(53%比 75%;P=0.034)、辅助性主要(57%比 77%;P=0.017)和继发性功能(57%比 77%;P=0.026)通畅率也是如此。多变量 Cox 回归显示,一期手术的失败风险高 3.2 倍(P=0.028)。男性更有可能失去通路(风险比为 2.7 倍;P=0.054)。

结论

本研究描述了大量的 BBAVF,并对一期和两期手术进行了广泛比较。两期手术的整体功能通畅率显著提高。

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