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2
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3
Global iodine status in 2011 and trends over the past decade.2011 年全球碘状况及过去十年的变化趋势。
J Nutr. 2012 Apr;142(4):744-50. doi: 10.3945/jn.111.149393. Epub 2012 Feb 29.
4
Iodine deficiency disorders among primary school children in eastern Nepal.尼泊尔东部小学生碘缺乏症。
Indian J Pediatr. 2011 Jan;78(1):45-8. doi: 10.1007/s12098-010-0239-2. Epub 2010 Oct 2.
5
Iodine-deficiency disorders.碘缺乏症
Lancet. 2008 Oct 4;372(9645):1251-62. doi: 10.1016/S0140-6736(08)61005-3.
6
Insufficient level of iodine content in household powder salt in Nepal.尼泊尔家用碘盐的碘含量水平不足。
Nepal Med Coll J. 2007 Jun;9(2):75-8.
7
Estimation of iodine in salt fortified with iodine & iron.碘铁强化盐中碘的测定
Indian J Med Res. 2006 Apr;123(4):531-40.
8
Seasonality in urinary and household salt iodine content among pregnant and lactating women of the plains of Nepal.尼泊尔平原地区孕妇和哺乳期妇女尿碘及家庭盐碘含量的季节性变化
Eur J Clin Nutr. 2003 Aug;57(8):969-76. doi: 10.1038/sj.ejcn.1601632.
9
Validation of spot-testing kits to determine iodine content in salt.用于测定盐中碘含量的现场检测试剂盒的验证
Bull World Health Organ. 2000;78(8):975-80.

使用快速检测试剂盒和碘量滴定法估算家庭食盐碘含量。

Household salt iodine content estimation with the use of rapid test kits and iodometric titration methods.

作者信息

Nepal Ashwini Kumar, Raj Shakya Prem, Gelal Basanta, Lamsal Madhab, Brodie David A, Baral Nirmal

机构信息

Research Assistant, Department of Biochemistry, B.P. Koirala Institute of Health Sciences , Dharan, Nepal .

出版信息

J Clin Diagn Res. 2013 May;7(5):892-5. doi: 10.7860/JCDR/2013/5477.2969. Epub 2013 Mar 25.

DOI:10.7860/JCDR/2013/5477.2969
PMID:23814736
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3681063/
Abstract

BACKGROUND

Universal salt iodization remains the best strategy for controlling iodine deficiency disorders in Nepal.

AIMS

This study was designed to study the salt types and the household salt iodine content of school aged children in the hilly and the plain districts of eastern Nepal.

MATERIAL AND METHODS

This cross-sectional study was carried out on school children of seven randomly chosen schools from four districts, namely, Sunsari, Dhankuta, Sankhuwasabha and Tehrathum of eastern Nepal. The school children were requested to bring two teaspoonfuls (approx. 12-15 g) of the salt which was consumed in their households, in a tightly sealed plastic pouch. The salt types were categorized, and the salt iodine content was estimated by using rapid test kits and iodometric titrations. The association of the salt iodine content of the different districts were tested by using the Chi-square test. The sensitivity, specificity, positive predictive values, and negative predictive values of the rapid test kits were compared with the iodometric titrations.

RESULTS

Our study showed that mean±SD values of the salt iodine content in the four districts, namely, Sunsari, Dhankuta, Sankhuwasabha and Tehrathum were 34.2±17.9, 33.2±14.5, 27.4±15.1 and 48.4±15.6 parts per million (ppm). There were 270 (38.2%) households which consumed crystal salt and 437(61.8%) of the households consumed packet salts.

CONCLUSIONS

Our study recommends a regular monitoring of the salt iodization programs in these regions. More families should be made aware of the need to ensure that each individual consumes iodized salt.

摘要

背景

全民食盐加碘仍然是尼泊尔控制碘缺乏病的最佳策略。

目的

本研究旨在调查尼泊尔东部山区和平原地区学龄儿童家庭食用盐的种类及碘含量。

材料与方法

本横断面研究选取了尼泊尔东部四个县(孙萨里、丹库塔、桑库瓦萨巴和特莱图姆)中随机抽取的七所学校的学童。要求学童用密封塑料袋带来两茶匙(约12 - 15克)家中食用的盐。对盐的种类进行分类,并用快速检测试剂盒和碘量滴定法估算盐碘含量。采用卡方检验检测不同地区盐碘含量的相关性。将快速检测试剂盒的灵敏度、特异性、阳性预测值和阴性预测值与碘量滴定法进行比较。

结果

我们的研究表明,孙萨里、丹库塔、桑库瓦萨巴和特莱图姆四个县盐碘含量的均值±标准差分别为34.2±17.9、33.2±14.5、27.4±15.1和48.4±15.6ppm。有270户(38.2%)家庭食用晶体盐,437户(61.8%)家庭食用袋装盐。

结论

我们的研究建议对这些地区的食盐加碘项目进行定期监测。应让更多家庭意识到确保每个人食用加碘盐的必要性。