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用于预测经皮肾镜取石术后无结石率的首尔国立大学肾结石复杂性评分

Seoul National University Renal Stone Complexity Score for Predicting Stone-Free Rate after Percutaneous Nephrolithotomy.

作者信息

Jeong Chang Wook, Jung Jin-Woo, Cha Woo Heon, Lee Byung Ki, Lee Sangchul, Jeong Seong Jin, Hong Sung Kyu, Byun Seok-Soo, Lee Sang Eun

机构信息

Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea ; Department of Urology, College of Medicine, Seoul National University, Seoul, Korea.

出版信息

PLoS One. 2013 Jun 18;8(6):e65888. doi: 10.1371/journal.pone.0065888. Print 2013.

Abstract

OBJECTIVES

Currently, no standardized method is available to predict success rate after percutaneous nephrolithotomy. We devised and validated the Seoul National University Renal Stone Complexity (S-ReSC) scoring system for predicting the stone-free rate after single-tract percutaneous nephrolithotomy (sPCNL).

PATIENTS AND METHODS

The data of 155 consecutive patients who underwent sPCNL were retrospectively analyzed. Preoperative computed tomography images were reviewed. The S-ReSC score was assigned from 1 to 9 based on the number of sites involved in the renal pelvis (#1), superior and inferior major calyceal groups (#2-3), and anterior and posterior minor calyceal groups of the superior (#4-5), middle (#6-7), and inferior calyx (#8-9). The inter- and intra-observer agreements were accessed using the weighted kappa (κ). The stone-free rate and complication rate were evaluated according to the S-ReSC score. The predictive accuracy of the S-ReSC score was assessed using the area under the receiver operating characteristic curve (AUC).

RESULTS

The overall SFR was 72.3%. The mean S-ReSC score was 3.15±2.1. The weighted kappas for the inter- and intra-observer agreements were 0.832 and 0.982, respectively. The SFRs in low (1 and 2), medium (3 and 4), and high (5 or higher) S-ReSC scores were 96.0%, 69.0%, and 28.9%, respectively (p<0.001). The predictive accuracy was very high (AUC 0.860). After adjusting for other variables, the S-ReSC score was still a significant predictor of the SFR by multiple logistic regression. The complication rates were increased to low (18.7%), medium (28.6%), and high (34.2%) (p = 0.166).

CONCLUSIONS

The S-ReSC scoring system is easy to use and reproducible. This score accurately predicts the stone-free rate after sPCNL. Furthermore, this score represents the complexity of surgery.

摘要

目的

目前,尚无标准化方法可用于预测经皮肾镜取石术后的成功率。我们设计并验证了首尔国立大学肾结石复杂性(S-ReSC)评分系统,用于预测单通道经皮肾镜取石术(sPCNL)后的无石率。

患者与方法

对155例连续接受sPCNL的患者的数据进行回顾性分析。回顾术前计算机断层扫描图像。根据肾盂受累部位数量(#1)、上下大肾盏组(#2 - 3)以及上极(#4 - 5)、中极(#6 - 7)和下极(#8 - 9)的前后小肾盏组,将S-ReSC评分定为1至9分。采用加权kappa(κ)系数评估观察者间和观察者内的一致性。根据S-ReSC评分评估无石率和并发症发生率。使用受试者工作特征曲线下面积(AUC)评估S-ReSC评分的预测准确性。

结果

总体无石率为72.3%。S-ReSC评分的平均值为3.15±2.1。观察者间和观察者内一致性的加权kappa系数分别为0.832和0.982。S-ReSC低评分(1分和2分)、中评分(3分和4分)和高评分(5分及以上)患者的无石率分别为96.0%、69.0%和28.9%(p<0.001)。预测准确性非常高(AUC为0.860)。在对其他变量进行校正后,通过多因素逻辑回归分析,S-ReSC评分仍是无石率的显著预测指标。并发症发生率分别升至低评分组(18.7%)、中评分组(28.6%)和高评分组(34.2%)(p = 0.166)。

结论

S-ReSC评分系统易于使用且可重复。该评分可准确预测sPCNL术后的无石率。此外,该评分还能反映手术的复杂性。

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