Ali Nadir Ali Mohamed, George Joshua, Joshi Nayan, Chong Elizabeth
Department of Ophthalmology, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam.
Int J Ophthalmol. 2013 Jun 18;6(3):381-4. doi: 10.3980/J.ISSN.2222-3959.2013.03.23. Print 2013.
To identify the prevalence of retinopathy of prematurity (ROP) among preterm neonates admitted to Department of Neonatology, RIPAS hospital, Brunei Darussalam.
We studied 67 preterm infants fulfilling the eligibility criteria for ROP screening. All infants studied were admitted to the Department of Neonatology, RIPAS Hospital, within a period of one year. Birth weight (BW), gestational age (GA), corrected age at each review, initial and final diagnoses and number of reviews required was recorded for each infant. Infants were followed up two weekly until they reach a corrected age of 40 weeks or complete vascularization was noted. Prevalence of ROP was identified. Descriptive analysis, regression analysis and independent-sample t-test were used to statistically check for differences between ROP and non-ROP groups.
A total number of 201 ROP screenings were carried out for 67 preterm infants. Males outnumbered females (56.7%). The mean number of reviews per child was (3.19±1.1) times (range: 1-6 times), the mean GA among the preterm babies examined was (29.5±2.6) weeks (range: 23-36 weeks), and the mean BW was 1300±500g (range: 660-3600g). The prevalence of ROP among the examined infants was 34.8%. Prevalence of threshold disease that required laser treatment was 25.4%. Prevalence of ROP among those with extremely low BW was 86.7% compared to 27.8% in those with very low BW. Respiratory distress and congenital heart diseases were significantly associated with higher incidence of ROP.
Lower BW, lower GA and female gender are associated with higher risk of developing ROP among preterm infants in Brunei Darussalam.
确定文莱达鲁萨兰国里帕斯医院新生儿科收治的早产儿中早产儿视网膜病变（ROP）的患病率。
我们研究了67名符合ROP筛查资格标准的早产儿。所有研究的婴儿均在一年内入住里帕斯医院新生儿科。记录每个婴儿的出生体重（BW）、胎龄（GA）、每次复查时的矫正年龄、初始和最终诊断以及所需复查次数。婴儿每两周随访一次，直至达到40周矫正年龄或观察到血管完全形成。确定ROP的患病率。采用描述性分析、回归分析和独立样本t检验对ROP组和非ROP组之间的差异进行统计学检验。
对67名早产儿共进行了201次ROP筛查。男性多于女性（56.7%）。每个儿童的平均复查次数为（3.19±1.1）次（范围：1 - 6次），接受检查的早产儿的平均GA为（29.5±2.6）周（范围：23 - 36周），平均BW为1300±500g（范围：660 - 3600g）。受检婴儿中ROP的患病率为34.8%。需要激光治疗的阈值疾病患病率为25.4%。极低出生体重儿中ROP的患病率为86.7%，而超低出生体重儿中为27.8%。呼吸窘迫和先天性心脏病与ROP的较高发病率显著相关。
在文莱达鲁萨兰国，较低的出生体重、较低的胎龄和女性性别与早产儿发生ROP的较高风险相关。
