Département d'Obstétrique, Gynécologie et Reproduction, Université Laval, 2325, Rue de l'Université, Québec, QC, G1V 0A6, Canada.
Syst Rev. 2013 Jul 4;2:50. doi: 10.1186/2046-4053-2-50.
Hysterosalpingosonography has been suggested as a less invasive alternative to hysterosalpingography for detecting tubal occlusion among subfertile women. We aim to determine the diagnostic accuracy of hysterosalpingosonography and to compare it to hysterosalpingography.
METHODS/DESIGN: We will conduct a systematic review of diagnostic test accuracy. We will search Medline, Embase, Cochrane Library, Web of Science and Biosis, as well as reference lists of included studies and previous related review articles. Diagnostic studies that compared hysterosalpingosonography ± hysterosalpingography to laparoscopy with chromotubation in women suffering from subfertility will be eligible. Two authors will independently screen for inclusion, data extraction, and quality assessment. Methodological quality will be assessed using the Quality Assessment of Diagnostic Accuracy Study 2 tool (QUADAS-2). We will use SAS 9.3 (SAS Institute Inc., Cary, NC, USA, 2011) to program bivariate random-effects models, estimate pooled sensitivity and specificity with 95% confidence intervals and to generate summary receiver operating characteristics curves. We will perform sensitivity analyses to examine the effect of differences in techniques used for hysterosalpingosonography and in methodological quality of studies.
This systematic review will help to determine if hysterosalpingosonography is an adequate alternative screening test for diagnosing tubal occlusion. Accuracy of specific sono-HSG techniques may also be identified.
This review has been registered at PROSPERO. The registration number is CRD42013003829.
子宫输卵管超声造影术被认为是一种较子宫输卵管造影术创伤性更小的方法，可用于检测不孕女性的输卵管阻塞。我们旨在确定子宫输卵管超声造影术的诊断准确性，并将其与子宫输卵管造影术进行比较。
方法/设计：我们将进行系统的诊断测试准确性评价。我们将检索 Medline、Embase、Cochrane 图书馆、Web of Science 和 Biosis，以及纳入研究的参考文献列表和之前的相关综述文章。符合条件的诊断研究将比较子宫输卵管超声造影术±子宫输卵管造影术与腹腔镜下输卵管通液术在不孕女性中的诊断准确性。两名作者将独立筛选纳入、数据提取和质量评估。使用 QUADAS-2 工具评估方法学质量。我们将使用 SAS 9.3（SAS Institute Inc.，Cary，NC，USA，2011）编程双变量随机效应模型，估计合并的敏感性和特异性及其 95%置信区间，并生成综合受试者工作特征曲线。我们将进行敏感性分析，以检查子宫输卵管超声造影术使用技术和研究方法学质量差异的影响。
本系统评价将有助于确定子宫输卵管超声造影术是否是诊断输卵管阻塞的一种合适的替代筛查试验。也可能确定特定的超声子宫输卵管造影术技术的准确性。
本综述已在 PROSPERO 上注册。注册号为 CRD42013003829。
