Duksal Fatma, Akcay Ahmet, Becerir Tulay, Ergin Ahmet, Becerir Cem, Guler Nermin
Cumhuriyet University, Cumhuriyet School of Medicine, Department of Pediatrics, Division of Pediatric Allergy, Sivas, Turkey.
Int J Pediatr Otorhinolaryngol. 2013 Sep;77(9):1434-9. doi: 10.1016/j.ijporl.2013.05.038. Epub 2013 Jul 2.
To assess the time trends and possible risk factors associated with allergic rhinitis symptoms in schoolchildren from Denizli, Turkey.
Two identical cross-sectional surveys were performed in the 13- to 14-yr age group at intervals of six years using ISAAC questionnaire. Possible risk factors were also asked and the children completed questionnaires by self.
A total of 4078 children (response rate 75%) in the 2008 and 3004 children (response rate, 93.8%) in 2002 were included. The lifetime prevalence of rhinitis, 12-month prevalence of rhinitis, prevalence of associated itchy eye in the previous 12 months and doctor diagnosed allergic rhinitis prevalence were increased from 34.2% to 49.4% (POR=1.87, 95% CI=47.8-50.9 and p ≤ 0.001), from 23.5.0% to 32.9% (POR=1.59, 95% CI=31.4-34.3 and p ≤ 0.001), from 9.6% to 14.9% (POR=1.64, 95% CI=13.8-16.0 and p ≤ 0.001), and from 4.3% to 7% (POR=1.67, 95% CI=6.2-7.8 and p ≤ 0.001) respectively. Severe interference with daily activity in the previous 12 months did not change. In multivariate analysis, history of family atopy, stuffed toys, high annual family income, presence of allergy in mother, father and accompaniment of children to their parents after school hours in textile industry were found as risk factors in 2008 study.
The prevalence of allergic rhinitis increased significantly in 2008. Family history of atopy, stuffed toys, high annual family income and accompaniment of children to their parents in textile industry were found as risk factors for doctor diagnosed allergic rhinitis.
评估土耳其代尼兹利学龄儿童过敏性鼻炎症状的时间趋势及相关危险因素。
采用国际儿童哮喘和过敏研究（ISAAC）问卷，对13至14岁年龄组的儿童每隔六年进行两次相同的横断面调查。同时询问可能的危险因素，由儿童自行完成问卷。
2008年共纳入4078名儿童（应答率75%），2002年纳入3004名儿童（应答率93.8%）。鼻炎的终生患病率、鼻炎的12个月患病率、过去12个月相关眼痒的患病率以及医生诊断的过敏性鼻炎患病率分别从34.2%增至49.4%（比值比[POR]=1.87，95%置信区间[CI]=47.8 - 50.9，p≤0.001），从23.5%增至32.9%（POR=1.59，95% CI=31.4 - 34.3，p≤0.001），从9.6%增至14.9%（POR=1.64，95% CI=13.8 - 16.0，p≤0.001），以及从4.3%增至7%（POR=1.67，95% CI=6.2 - 7.8，p≤0.001）。过去12个月对日常活动的严重干扰未发生变化。在多变量分析中，2008年的研究发现，家族特应性病史、填充玩具、家庭年收入高、母亲患有过敏症、父亲患有过敏症以及儿童放学后在纺织行业随父母一起，均为危险因素。
2008年过敏性鼻炎患病率显著增加。家族特应性病史、填充玩具、家庭年收入高以及儿童在纺织行业随父母一起，被发现是医生诊断过敏性鼻炎的危险因素。
