Batlles-Garrido J, Torres-Borrego J, Rubí-Ruiz T, Bonillo-Perales A, González-Jiménez Y, Momblán-De Cabo J, Aguirre-Rodríguez J, Losillas-Maldonado A, Torres-Daza M
Paediatric Pulmonology and Allergy Unit, Service of Paediatrics, Hospital Torrecárdenas, Almería, Spain.
Allergol Immunopathol (Madr). 2010 May-Jun;38(3):135-41. doi: 10.1016/j.aller.2009.09.005. Epub 2010 May 11.
Allergic rhinitis affects 10-30% of children in developed countries and has increased in frequency over the last few decades, probably due to changes in the environment and life style.
To assess the prevalence, severity, and factors linked to rhinitis in 10 and 11-year-old children from Almeria (Spain).
As part of ISAAC II, a cross-sectional survey was conducted among a representative sample of 1143 schoolchildren in spring and autumn of 2001, using homologated questionnaires and skin-prick testing.
The overall prevalence of rhinitis and rhinoconjunctivitis were 38.9% and 24.8%, respectively, 17.9% had medically diagnosed rhinitis. During the previous year symptoms disturbed daily activities and school attendance in some measure in 40% and 26% of children with rhinitis, respectively. The risk factors found in the multiple logistic regression analysis were atopy (OR 2.57; 95% CI 1.92-3.42); cat contact at home during first year of life (OR 2.4 95% CI 1.13-5.12); prior medical diagnosis of asthma (OR 2.2; 95% CI 1.22-4.02); nocturnal cough in absence of colds (OR 1.9; 95% CI 1.25-2.97); diagnosis of rhinitis in one of the parents (OR 1.8; 95% CI 1.31-2.59); wheezing at any time (OR 1.6; 95% CI 1.18-2.28); and nursery school attendance (OR 1.5; 95% CI 1.21-2.5).
The prevalence of rhinitis found is superior to that of other centres participating in the ISAAC Phases I and II, and coexists with asthma and eczema in many children. The independent risk factors associated to rhinitis are in accordance with previous reports.
在发达国家,过敏性鼻炎影响着10%至30%的儿童,且在过去几十年中发病率有所上升,这可能归因于环境和生活方式的改变。
评估西班牙阿尔梅里亚10岁和11岁儿童鼻炎的患病率、严重程度及相关因素。
作为国际儿童哮喘及过敏研究(ISAAC)二期的一部分,于2001年春秋两季对1143名学童的代表性样本进行了横断面调查,采用标准化问卷和皮肤点刺试验。
鼻炎和鼻结膜炎的总体患病率分别为38.9%和24.8%,17.9%的儿童经医学诊断患有鼻炎。在前一年,分别有40%和26%的鼻炎儿童症状在一定程度上影响了日常活动和上学出勤率。多因素逻辑回归分析发现的危险因素包括特应性(比值比[OR]2.57;95%可信区间[CI]1.92 - 3.42);1岁以内家中养猫(OR 2.4;95%CI 1.13 - 5.12);既往哮喘医学诊断(OR 2.2;95%CI 1.22 - 4.02);无感冒时夜间咳嗽(OR 1.9;95%CI 1.25 - 2.97);父母一方有鼻炎诊断(OR 1.8;95%CI 1.31 - 2.59);曾有喘息(OR 1.6;95%CI 1.18 - 2.28);上过幼儿园(OR 1.5;95%CI 1.21 - 2.5)。
所发现的鼻炎患病率高于参与ISAAC一期和二期的其他中心,且在许多儿童中与哮喘和湿疹并存。与鼻炎相关的独立危险因素与先前报道一致。