Uemura Tomohiro, Nakano Akihiko
Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Histochem Cell Biol. 2013 Sep;140(3):341-5. doi: 10.1007/s00418-013-1116-7. Epub 2013 Jul 6.
In all eukaryotic cells, a membrane trafficking system connects the post-Golgi organelles, including the trans-Golgi network (TGN), endosomes, and vacuoles. This complex network plays critical roles in several higher-order functions in multicellular organisms. The TGN, one of the important organelles for protein transport in the post-Golgi network, functions as a sorting station, where cargo proteins are directed to the appropriate post-Golgi compartments. The TGN has been considered to be a compartment belonging to the Golgi apparatus, located on the trans side of the Golgi apparatus. However, in plant cells, recent studies have suggested that the TGN is an independent, dynamic organelle that possesses features different than those of TGNs in animal and yeast cells. In this review, we summarize recent progress regarding the dynamics and physiological functions of the plant TGN.
在所有真核细胞中，一个膜运输系统连接了高尔基体后细胞器，包括反式高尔基体网络（TGN）、内体和液泡。这个复杂的网络在多细胞生物的几个高阶功能中发挥着关键作用。TGN是高尔基体后网络中蛋白质运输的重要细胞器之一，作为一个分拣站，货物蛋白在此被导向适当的高尔基体后区室。TGN一直被认为是属于高尔基体的一个区室，位于高尔基体的反式面。然而，在植物细胞中，最近的研究表明，TGN是一个独立的、动态的细胞器，具有与动物和酵母细胞中的TGN不同的特征。在这篇综述中，我们总结了关于植物TGN的动态和生理功能的最新进展。
