口腔颌面外科中的富血小板生长因子。
Platelet-rich growth factor in oral and maxillofacial surgery.
作者信息
Pal Uma Shanker, Mohammad Shadab, Singh Rakesh K, Das Somdipto, Singh Nimisha, Singh Mayank
机构信息
Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.
出版信息
Natl J Maxillofac Surg. 2012 Jul;3(2):118-23. doi: 10.4103/0975-5950.111340.
Abstract
Platelet-rich growth factor is an innovative regenerative therapy used to promote hard and soft tissue healing. It involves the application of autologous platelet-leukocyte-rich plasma containing growth factors and thrombin directly to the site of treatment. It is the intrinsic growth factors released by activated platelets which are concentrated in a topical gel formula. Clinically, it is an affordable treatment with potentially broad spectrum of applications in maxillofacial surgery especially in the treatment of complex or refractory wounds. The present article reviews its various applications not only in the specialization of oral and maxillofacial surgery but also in regenerative medicine.
摘要
富含血小板生长因子是一种用于促进软硬组织愈合的创新再生疗法。它涉及将含有生长因子和凝血酶的自体富血小板白细胞血浆直接应用于治疗部位。它是活化血小板释放的内在生长因子，这些因子浓缩在一种局部凝胶配方中。临床上，它是一种经济实惠的治疗方法，在颌面外科尤其是治疗复杂或难治性伤口方面具有潜在的广泛应用。本文不仅综述了其在口腔颌面外科专业领域的各种应用，还介绍了其在再生医学中的应用。
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