Guha Poulomi, Solete Pradeep, Antony Delphine, Arun Nishitha, Karobari Mohmed Isaqali, Ramamoorthi Surendar
Department of Conservative Dentistry and Endodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Department of Dentistry, Ministry of Health, Qassim Health Cluster, King Saud Hospital, Unaizah, Al Qassim, Saudi Arabia.
J Conserv Dent Endod. 2025 May;28(5):412-419. doi: 10.4103/JCDE.JCDE_4_25. Epub 2025 May 6.
The success of endodontic therapy is primarily determined by effective root canal obturation and complete bacterial eradication. Recently, bioceramic sealers have gained significant attention in root canal treatments due to their bioactive and biocompatible properties. This study aims to characterize a novel bioactive glass-based bioceramic sealer, utilizing X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy to evaluate its bioactivity and hydroxyapatite-forming potential.
Characterization of the material involved XRD to identify crystalline phases, while FTIR was employed to detect functional groups. The synthesized powder was sieved and pressed into discs for FTIR analysis, with XRD analysis conducted on the sieved powder.
XRD analysis revealed nanoscale crystalline features, indicating a complex multiphase composition. FTIR identified silicate networks, hydroxyl groups, and carbonate species, supporting the material's bioactivity and its potential to form hydroxyapatite.
The bioactive glass-based bioceramic sealer shows strong potential for dental and orthopedic use. Its nanoscale crystalline structure and silicate network enhance bioactivity and mechanical strength, while hydroxyl and carbonate groups promote tissue integration and hydroxyapatite formation. Further and studies are needed to confirm its clinical effectiveness.
牙髓治疗的成功主要取决于有效的根管充填和彻底的细菌清除。近年来,生物陶瓷封闭剂因其生物活性和生物相容性在根管治疗中受到了广泛关注。本研究旨在对一种新型的基于生物活性玻璃的生物陶瓷封闭剂进行表征,利用X射线衍射(XRD)和傅里叶变换红外(FTIR)光谱来评估其生物活性和形成羟基磷灰石的潜力。
对该材料的表征包括利用XRD识别晶相,同时采用FTIR检测官能团。将合成的粉末过筛并压制成圆盘用于FTIR分析,对过筛后的粉末进行XRD分析。
XRD分析揭示了纳米级的晶体特征,表明其具有复杂的多相组成。FTIR识别出了硅酸盐网络、羟基和碳酸盐物种,支持了该材料的生物活性及其形成羟基磷灰石的潜力。
基于生物活性玻璃的生物陶瓷封闭剂在牙科和骨科应用中显示出强大的潜力。其纳米级晶体结构和硅酸盐网络增强了生物活性和机械强度,而羟基和碳酸盐基团促进了组织整合和羟基磷灰石的形成。需要进一步的研究来证实其临床有效性。